Q54PV7
Gene name |
eif2a (DDB_G0284267) |
Protein name |
Eukaryotic translation initiation factor 2A |
Names |
eIF-2A |
Species |
Dictyostelium discoideum (Slime mold) |
KEGG Pathway |
ddi:DDB_G0284267 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q54PV7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q54PV7-F1 | Predicted | AlphaFoldDB |
No variants for Q54PV7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q54PV7 | |||||
No associated diseases with Q54PV7
1 regional properties for Q54PV7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Translation initiation factor, beta propellor-like domain | 258 - 447 | IPR013979 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosolic small ribosomal subunit | The small subunit of a ribosome located in the cytosol. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| mRNA binding | Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns. |
| ribosome binding | Binding to a ribosome. |
| translation initiation factor activity | Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide. |
| tRNA binding | Binding to a transfer RNA. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| translational initiation | The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSAPNNNNNN | TTTTTTTSPS | PSQSSPTLTS | VASNSTTTTT | TETLTTPKLQ | FVVRSKTNAY |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QEIGQQYGKN | LNLPSYSNGD | CRHVEYSKDG | TLIAYVNLNE | IVICNSDGGS | VHSVINRPNV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GMISFSPQNS | FLLTWERMSE | YNNNENNLIV | WDIKQASILY | KTSQKYCNQE | NWPLIKWTDD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EVLAGKLISN | EVHFFNGRSI | GVLAKKIKLQ | DISSFEFAPA | TNGGPYKIAT | FVPEKGSTPG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SARIYSYPTV | NEYCSHLKFF | KASEAKVLWN | KKGNAILVHT | FTDTDKSGKS | YYGETGLWFL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SQDGSSFNLN | IKGPIHDVQW | SPTLDQFMVC | YGNMPSQTTL | FNLKGEPLVD | FGLNPRNTIR |
| 370 | 380 | 390 | 400 | 410 | 420 |
| FSPNGQLLCL | GGFGNLQGDM | DFWDLTRYKR | ICGTQSHCAI | YTEWSADSVH | FMTAVLSPRI |
| 430 | 440 | 450 | 460 | 470 | 480 |
| RVDNGVKIIK | YDNTIVYQEN | IPELYQASWR | PLNPLVFPNE | RIVYPSIQQQ | KESSPQPQKY |
| 490 | 500 | 510 | 520 | 530 | 540 |
| TPPSLRNMQA | APPVVTSPPA | MGAPLPSGFK | VYLASAKSSS | TFKPKQKPSS | TTTTNNTTTT |
| 550 | 560 | 570 | 580 | 590 | 600 |
| TTKPAADEPK | RELTPIEKKI | RNVERKLKEV | EVLKEKLNSG | EFIPPTAIEK | INNEQKFLEE |
| LRKLQSEL |