Q54PT2
Gene name |
vps4 (DDB_G0284347) |
Protein name |
Vacuolar protein sorting-associated protein 4 |
Names |
|
Species |
Dictyostelium discoideum (Slime mold) |
KEGG Pathway |
ddi:DDB_G0284347 |
EC number |
3.6.4.6: Acting on ATP; involved in cellular and subcellular movement |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q54PT2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q54PT2-F1 | Predicted | AlphaFoldDB |
No variants for Q54PT2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q54PT2 | |||||
No associated diseases with Q54PT2
7 regional properties for Q54PT2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | AAA+ ATPase domain | 167 - 302 | IPR003593 |
| domain | ATPase, AAA-type, core | 171 - 299 | IPR003959 |
| conserved_site | ATPase, AAA-type, conserved site | 272 - 291 | IPR003960 |
| domain | MIT domain | 3 - 81 | IPR007330 |
| domain | Spastin/Vps4, C-terminal | 381 - 440 | IPR015415 |
| domain | AAA ATPase, AAA+ lid domain | 325 - 354 | IPR041569 |
| domain | Vacuolar protein sorting-associated protein 4, MIT domain | 5 - 79 | IPR045253 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.6.4.6 | Acting on ATP; involved in cellular and subcellular movement |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| endosome | A vacuole to which materials ingested by endocytosis are delivered. |
| endosome membrane | The lipid bilayer surrounding an endosome. |
| pathogen-containing vacuole | A membrane-bound intracellular compartment that is formed upon internalization of a pathogen into a host cell, and in which the pathogen resides. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| endosomal transport | The directed movement of substances mediated by an endosome, a membrane-bounded organelle that carries materials enclosed in the lumen or located in the endosomal membrane. |
| protein transport | The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| response to bacterium | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium. |
| response to wounding | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism. |
| vacuole organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGDVNFLQKA | IQIVQQATEQ | DNAKNYAEAH | RLYIQSLEWF | TTALKYEKSE | RSKATIKAKT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LEYLQRAEQL | KEYLDKSKNK | KPVAVGGNKS | NSAGSANGAG | KSAKEDDEDM | DPEDKKRNDS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LSSSIVTTKP | NVKWDDVAGL | YQAKEYLKEA | VIFPIKFPQM | FTGNRKPWKG | ILLYGPPGTG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KSYLAKAVAT | EISSTFFSIS | PSDIVTKWLG | DSEKLVKQLF | EMAREKNNSV | IFIDEVDSLC |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SSRNDQESES | ARRIKTEFLI | QMNGVGNDSD | GILVLAATNI | PWGLDLAIRR | RFEKRIYIGL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| PEPQARAKMF | QIHIGSTPNT | LVQADYKKLA | DLTEGYSGSD | IGSLVKDAIM | QPVRAVQCAT |
| 370 | 380 | 390 | 400 | 410 | 420 |
| HFKQIRAPSR | EDPSVMTDYV | TPCSPGDPLA | QEMTWMDIDP | TKLKEPEITI | ADCLKSLRVI |
| 430 | 440 | ||||
| KPSVNKADLD | RYVEFTNDFG | QDGV |