Q54N47

PR
Gene name
bcaA (DDB_G0285509)
Protein name
Branched-chain-amino-acid aminotransferase
Names
Species
Dictyostelium discoideum (Slime mold)
KEGG Pathway
ddi:DDB_G0285509
EC number
2.6.1.42: Transaminases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-67 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q54N47

Entry ID Method Resolution Chain Position Source
AF-Q54N47-F1 Predicted AlphaFoldDB

No variants for Q54N47

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q54N47

No associated diseases with Q54N47

1 regional properties for Q54N47

Type Name Position InterPro Accession
conserved_site Aminotransferase, class IV, conserved site 246 - 281 IPR018300

Functions

Description
EC Number 2.6.1.42 Transaminases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

5 GO annotations of molecular function

Name Definition
branched-chain-amino-acid transaminase activity Catalysis of the reaction: a branched-chain amino acid + 2-oxoglutarate = L-glutamate + a 2-oxocarboxylate derived from the branched-chain amino acid.
L-isoleucine transaminase activity Catalysis of the reaction: 2-oxoglutarate + L-isoleucine = (S)-3-methyl-2-oxopentanoic acid + L-glutamic acid.
L-leucine transaminase activity Catalysis of the reaction: 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamatic acid.
L-leucine:2-oxoglutarate aminotransferase activity Catalysis of the reaction: L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate.
L-valine transaminase activity Catalysis of the reaction: 2-oxoglutarate + L-valine = 3-methyl-2-oxobutanoic acid + L-glutamatic acid.

2 GO annotations of biological process

Name Definition
branched-chain amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
cellular amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MFGRFIRQYS TSKNIINVNE LIVEKTKTPF QKYTDKTKLV FGKQFSDHMI EVQWTKEEGW
70 80 90 100 110 120
GVPKISGYHN LSIPPSASVL HYALECFEGM KAYKDSNGKI RLFRPDQNMN RFLNSAKRIC
130 140 150 160 170 180
LPEFNKEAVI ELIKKLCVLD KDWIPEGKGY SLYLRPTLIA TQNSLGVGAS NSALMFVIAS
190 200 210 220 230 240
PVGPYYPEGF KPVKLIADDQ YVRAWAGGSG AFKLGSNYAP TIFPQLEAAK KGFSQVLWLL
250 260 270 280 290 300
NDYVTEVGTM NMFVFWNNAQ GEKELITPPL GDGTILPGVT RDSILKLTQQ WGEFKITEKN
310 320 330 340 350 360
FTMTELAKAI KEGRVFEAFG AGTAAIVSPI ESISYKGENY SIPIDASLNC GPLTKRISDS
370
IMAIQYGETN SDWSVIVD