Q54KM9

PR
Gene name
rab11B (DDB_G0287211)
Protein name
Ras-related protein Rab-11B
Names
Species
Dictyostelium discoideum (Slime mold)
KEGG Pathway
ddi:DDB_G0287211
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

148-220 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q54KM9

Entry ID Method Resolution Chain Position Source
AF-Q54KM9-F1 Predicted AlphaFoldDB

No variants for Q54KM9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q54KM9

No associated diseases with Q54KM9

1 regional properties for Q54KM9

Type Name Position InterPro Accession
domain Small GTP-binding protein domain 11 - 169 IPR005225

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Lipid-anchor ; Cytoplasmic side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
early endosome A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.
phagocytic vesicle A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
nucleotide binding Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.

4 GO annotations of biological process

Name Definition
Golgi to endosome transport The directed movement of substances from the Golgi to early sorting endosomes. Clathrin vesicles transport substances from the trans-Golgi to endosomes.
intracellular protein transport The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
phagolysosome assembly involved in apoptotic cell clearance The process in which a phagosome, a vesicle formed by phagocytosis, fuses with a lysosome as a part of apoptotic cell clearance.
small GTPase mediated signal transduction The series of molecular signals in which a small monomeric GTPase relays a signal.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MVLKTIEYDY LCKIVVIGDS GVGKSNLLSR YNKNEFSVGK LSTIGVEFST KTLKIDNKLI
70 80 90 100 110 120
KLQLWDTAGQ EKYNSITESY YKGAIGALIV YNIADRNSFN NLEKWLKKFR ENAHQDYGIM
130 140 150 160 170 180
LVGNKSDLKE YREVSTLEGK QFAEKHYMQF IETSALDSNN VETAFNNLFN FIYYSLFKNK
190 200 210
TMTLDINNNG NNNSNIMVGD CEPIQFDQRY TINKPVYDCC