Q54KJ8

PR
Gene name
gtf2e2 (DDB_G0287307)
Protein name
General transcription factor IIE subunit 2
Names
Transcription initiation factor IIE subunit beta, TFIIE-beta
Species
Dictyostelium discoideum (Slime mold)
KEGG Pathway
ddi:DDB_G0287307
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-95 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q54KJ8

Entry ID Method Resolution Chain Position Source
AF-Q54KJ8-F1 Predicted AlphaFoldDB

No variants for Q54KJ8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q54KJ8

No associated diseases with Q54KJ8

2 regional properties for Q54KJ8

Type Name Position InterPro Accession
domain Transcription factor TFIIE beta subunit, DNA-binding domain 54 - 133 IPR003166
domain TFA2, Winged helix domain 2 133 - 190 IPR040501

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
transcription factor TFIIE complex A transcription factor which in humans consists of a complex of two alpha and two beta chains. Recruits TFIIH to the initiation complex and helps activate both RNA polymerase II and TFIIH.

1 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

1 GO annotations of biological process

Name Definition
transcription initiation at RNA polymerase II promoter A transcription initiation process that takes place at a RNA polymerase II gene promoter. Messenger RNAs (mRNA) genes, as well as some non-coding RNAs, are transcribed by RNA polymerase II.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNMAGFKETQ MKAIETLNSI KKPSSSTNSA FKYIPKISGG GGSSSANRQS SIYTANTLRD
70 80 90 100 110 120
KQVKEKPSNR IVYDIVNYLK TLEGIPADTK EIMHSTNHMI DDKPEILELL RNNEKIIDHG
130 140 150 160 170 180
NDRFSFKPKF NVRTQRDILD LLPNYPGGIL VSELAESYNN AESDVKKLKE TKQIFAIKAA
190 200 210 220 230 240
ESACDIIFPN DERLRVPLSS ELVDMWKSIK LPNEADLEKE MKDAGLSVVE SVESARQTKS
250 260 270
TKLKKERKKR ITKVTNTHIE NFNPNDDVPQ LGSKPI