Q54K69

PR
Gene name
rab7B (DDB_G0287553)
Protein name
Ras-related protein Rab-7B
Names
Species
Dictyostelium discoideum (Slime mold)
KEGG Pathway
ddi:DDB_G0287553
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

141-197 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q54K69

Entry ID Method Resolution Chain Position Source
AF-Q54K69-F1 Predicted AlphaFoldDB

No variants for Q54K69

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q54K69

No associated diseases with Q54K69

6 regional properties for Q54K69

Type Name Position InterPro Accession
domain Helix-hairpin-helix DNA-binding motif, class 1 4 - 23 IPR003583-1
domain Helix-hairpin-helix DNA-binding motif, class 1 37 - 56 IPR003583-2
domain AAA+ ATPase domain 99 - 293 IPR003593
domain DNA recombination and repair protein Rad51-like, C-terminal 65 - 322 IPR013632
domain DNA recombination and repair protein RecA, monomer-monomer interface 264 - 316 IPR020587
domain DNA recombination and repair protein RecA-like, ATP-binding domain 78 - 259 IPR020588

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
late endosome A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
lysosome A small lytic vacuole that has cell cycle-independent morphology found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
phagocytic vesicle A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.

2 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.

2 GO annotations of biological process

Name Definition
phagosome-lysosome fusion The creation of a phagolysosome from a phagosome and a lysosome.
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTKGRKIIKV VIIGEKSVGK TSILRRYVDK RFVTLKPTIG VDFVMVSENM VTLQLWDTSG
70 80 90 100 110 120
QERFRSLEIS YYRGADYCIL VFDVTNEKTL YDLKLWRDDF IEKTEIRDPI LFPFIILGNK
130 140 150 160 170 180
IDDPNRVVTE KAAIQWCKDN IGGNLTYFDT SAKDNINIEQ VFKHISNQCE NQPQSNEIPP
190
EQLISLTEKK SNQSSCC