Q54K57

PR
Gene name
tpsA (DDB_G0287657)
Protein name
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] A
Names
Trehalose-6-phosphate synthase A, UDP-glucose-glucosephosphate glucosyltransferase A
Species
Dictyostelium discoideum (Slime mold)
KEGG Pathway
ddi:DDB_G0287657
EC number
2.4.1.15: Hexosyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

2-109 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q54K57

Entry ID Method Resolution Chain Position Source
AF-Q54K57-F1 Predicted AlphaFoldDB

No variants for Q54K57

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q54K57

No associated diseases with Q54K57

No regional properties for Q54K57

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q54K57

Functions

Description
EC Number 2.4.1.15 Hexosyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
alpha,alpha-trehalose-phosphate synthase complex (UDP-forming) A protein complex that possesses alpha,alpha-trehalose-phosphate synthase (UDP-forming) and trehalose-phosphatase activities, and thus catalyzes two reactions in trehalose biosynthesis. In the complex identified in Saccharomyces, Tps1p has alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity, Tps2p has trehalose 6-phosphate phosphatase activity; Tps3p is a regulatory subunit, and an additional subunit, Tsl1p, may be present.

2 GO annotations of molecular function

Name Definition
alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity Catalysis of the reaction: UDP-glucose + D-glucose-6-phosphate = UDP + alpha,alpha-trehalose-6-phosphate.
trehalose-phosphatase activity Catalysis of the reaction: trehalose 6-phosphate + H2O = trehalose + phosphate.

2 GO annotations of biological process

Name Definition
trehalose biosynthetic process The chemical reactions and pathways resulting in the formation of trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.
trehalose metabolism in response to stress The chemical reactions and pathways involving trehalose that occur as a result of a stimulus indicating the organism is under stress.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNENDNNLEN ETGFSGRLIV VSNRLPVSIK KESNGKWSCK MSSGGLVAAL SGLKSNFIWV
70 80 90 100 110 120
GWIGAEIEED DRKEIKELLW KDYSCIPVFL SEKVANEHYN GFSNGVLWPL FHYLPGDLDY
130 140 150 160 170 180
DDRIWNSYVE ANEQFSSVVA EILKPNDLVW VHDYHMMLLP EILKQKKPDA RIGFFLHIPF
190 200 210 220 230 240
PSSEIFRVLP CRKEILLGIL NCCLIGFHTY DYARHFLKSC TRIVGLETAP NGVYFKDRFV
250 260 270 280 290 300
QVGVFPVGID PDKFFESLKT TQVQNRIKEL KESFEGTKVL IGIDRLDYIK GIPQKLQAIE
310 320 330 340 350 360
RLFQKYPEWK GKLVLIQVAV PSRQDVEEYQ KLKKEVEELV GRINGLYGSI GYSPIHYLFQ
370 380 390 400 410 420
SVDPSELTAL YNISDAALIT SIRDGMNLVA QEYIVCQTEN NGVLILSEFT GAAQSLSGAV
430 440 450 460 470 480
MINPWNTEEV ADSIHNSLLM PPEEREEKHQ MLLKYVTKHT ASHWGLGFVK ELNKASSNTD
490 500 510 520 530 540
KMVTIQKLDI EKVVDIYKQS KRRLLIFAYD GTLIPYNNVP QLSRPSQELL NSFDILSNDP
550 560 570 580 590 600
KTDVYILSGR DKKTLSEWFL GIQIGLSAEY GCFFKLPEST EWEQQVPSMD LSWKETIRPL
610 620 630 640 650 660
FKYFTLRTPG SFFEEKEMLF TWHYRNADPI FGSIQARELH LHLDNLPLDV IVGDKTLGVR
670 680 690 700 710 720
SYNINPLSSM KKVITDTIPK GLDLILLIGD THIHPSELPT FDGKIFNISV GKKSVKDSYH
730
LSDPAEVNYL IIN