Q54GW3

PR
Gene name
DDB_G0289893
Protein name
Coiled-coil domain-containing protein 124 homolog
Names
Species
Dictyostelium discoideum (Slime mold)
KEGG Pathway
ddi:DDB_G0289893
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-247 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q54GW3

Entry ID Method Resolution Chain Position Source
AF-Q54GW3-F1 Predicted AlphaFoldDB

No variants for Q54GW3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q54GW3

No associated diseases with Q54GW3

No regional properties for Q54GW3

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q54GW3

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
transcription coactivator activity A transcription coregulator activity that activates or increases the transcription of specific gene sets via binding to a DNA-bound DNA-binding transcription factor, either on its own or as part of a complex. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coactivators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. A fourth class of coactivator activity is the bridging of a DNA-binding transcription factor to the general (basal) transcription machinery. The Mediator complex, which bridges sequence-specific DNA binding transcription factors and RNA polymerase, is also a transcription coactivator.

1 GO annotations of biological process

Name Definition
transcription by RNA polymerase II The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGGKKFGTNS KAEEARSKKA EVKKNENEKK QRDKEDKMWE ETDTKILDKQ KKQKEKEEKA
70 80 90 100 110 120
REDAKKKQEA KELLQQEDKE IKERYGKPSD TKVTRFEIQQ KRDKEQKQRE KELASRPSDP
130 140 150 160 170 180
RVVVVPTTTT TTTTTTTTTT GSDDHEEEDF NLEENMNHIL REQRLKDGKD VIDARDINEA
190 200 210 220 230 240
IGALSGNDGK EQHPERRMKA AFNAYEEENL PVLRKENPSL RLTQVKQLLW KNWLKAPENP
FNQVGSQ