Q54FH7
Gene name |
zmpste24 (DDB_G0290849) |
Protein name |
CAAX prenyl protease 1 homolog |
Names |
Prenyl protein-specific endoprotease 1 |
Species |
Dictyostelium discoideum (Slime mold) |
KEGG Pathway |
ddi:DDB_G0290849 |
EC number |
3.4.24.84: Metalloendopeptidases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q54FH7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q54FH7-F1 | Predicted | AlphaFoldDB |
No variants for Q54FH7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q54FH7 | |||||
No associated diseases with Q54FH7
Functions
| Description | ||
|---|---|---|
| EC Number | 3.4.24.84 | Metalloendopeptidases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of endoplasmic reticulum membrane | The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| metalloendopeptidase activity | Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| CAAX-box protein processing | The second process in a series of specific posttranslational modifications to the CAAX box region of CAAX box proteins, in which the last three amino acids of the protein (AAX) are removed by proteolysis. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVNYFIISIS | FFLLEHFYSF | YLNFRQSKLL | KNLTKVPEYC | KDRITQEDFK | KSQEYSKAKL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DYKTLTSTIQ | VLTTLLSFYY | PVYPYFWNLS | LELAEKIGYP | NEIIRSCFFF | AFTVGVSVIT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EIPFSYYYQF | ILEEKFGYNR | MTRTLFIKDK | IISTLLMIGF | GLPILSLAIF | IINWSGPQLW |
| 190 | 200 | 210 | 220 | 230 | 240 |
| FYCWLLLVAI | TLLSITIYPT | FIQPLFNKFT | PVDGELAESI | FALAKRVGFP | ASKDTIFVVD |
| 250 | 260 | 270 | 280 | 290 | 300 |
| NSKRDGHMNA | YFYGLFGTKR | IVLYDTLVNE | LDKEELLAVM | GHEFGHYKMS | HTLKQMLLVQ |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VHLVTLLYAF | SLLINDDQLY | QQFGFVSSKD | SVLVGLTLFM | FLYSPIDRIF | SLLINIFSRK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| YEFQADDFAV | ELGFLNSNHL | FKLHFKELGC | LVYDPLYSAY | HHSHPTLVER | SNNIDKKVAL |
| YKLKNK |