Q54EJ5
Gene name |
gloB2 (DDB_G0291482) |
Protein name |
Glyoxylase B2 |
Names |
|
Species |
Dictyostelium discoideum (Slime mold) |
KEGG Pathway |
ddi:DDB_G0291482 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q54EJ5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q54EJ5-F1 | Predicted | AlphaFoldDB |
No variants for Q54EJ5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q54EJ5 | |||||
No associated diseases with Q54EJ5
4 regional properties for Q54EJ5
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Aminoacyl-tRNA synthetase, class I, conserved site | 11 - 22 | IPR001412 |
| domain | Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain | 4 - 323 | IPR020058 |
| domain | Glutamyl-tRNA synthetase | 5 - 331 | IPR033910 |
| domain | Aminoacyl-tRNA synthetase, class I, anticodon-binding | 344 - 484 | IPR045462 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| hydroxyacylglutathione hydrolase activity | Catalysis of the reaction: (S)-(2-hydroxyacyl)glutathione + H2O = glutathione + a 2-hydroxy carboxylate. |
| metal ion binding | Binding to a metal ion. |
| sulfur dioxygenase activity | Catalysis of the reaction: sulfur + O2 + H2O = sulfite. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| glutathione metabolic process | The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle. |
| hydrogen sulfide metabolic process | The chemical reactions and pathways involving hydrogen sulfide, H2S. |
| methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione | The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into D-lactate via the intermediate S-lactoyl-glutathione. Glutathione is used in the first step of the pathway and then regenerated in the second step. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSNKAKIEVF | PELESATGQM | IIIDEQTKKC | AILDSVLNYT | QNNGRTSTKD | ADKLIAYIKE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NQLEPEWILE | THIHADHLSG | AHYLKGIYPN | AKTAIGEGAK | IVQKTFKTIY | NLEHTFPTDG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SQFDKLFTDD | ERFTIGSLQV | RVISTPGHTP | ACVSYYIEND | SVFVGDTMFM | PDVGTARCDF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PNGSAETLWT | SMKKILELPE | TVKVYVCHDY | PPQERGITFF | TTIAEQRLSN | KHIKDSVTKD |
| 250 | 260 | 270 | 280 | 290 | |
| EFIKMRTERD | ATLKAPQLLL | PSIQVNIRAG | ELPPKEDNGI | SYIKIPLNYL | KQ |