Q54DA7

PR
Gene name
rab4 (DDB_G0292406)
Protein name
Ras-related protein Rab-4
Names
Species
Dictyostelium discoideum (Slime mold)
KEGG Pathway
ddi:DDB_G0292406
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

145-205 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q54DA7

Entry ID Method Resolution Chain Position Source
AF-Q54DA7-F1 Predicted AlphaFoldDB

No variants for Q54DA7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q54DA7

No associated diseases with Q54DA7

1 regional properties for Q54DA7

Type Name Position InterPro Accession
domain Small GTP-binding protein domain 8 - 161 IPR005225

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Lipid-anchor ; Cytoplasmic side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
endosome A vacuole to which materials ingested by endocytosis are delivered.
pathogen-containing vacuole A membrane-bound intracellular compartment that is formed upon internalization of a pathogen into a host cell, and in which the pathogen resides.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
recycling endosome An organelle consisting of a network of tubules that functions in targeting molecules, such as receptors transporters and lipids, to the plasma membrane.

2 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.

4 GO annotations of biological process

Name Definition
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Rab protein signal transduction The series of molecular signals within the cell that are mediated by a member of the Rab family of proteins switching to a GTP-bound active state.
regulation of endocytosis Any process that modulates the frequency, rate or extent of endocytosis.
vesicle-mediated transport A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGKPLYLVKF IIIGSQSVGK SCLLFRFIDN KFKSQSTHTI GVDFSSRVVD IQGKNVKLQI
70 80 90 100 110 120
WDTAGQERFR SVVISYYRGS AGVALVYDVT NRESYNHITN WLSDVKSLAS PDVTIILVGN
130 140 150 160 170 180
KADLTEQREV TFLEASRIAQ ENGLLFMETS ALTGEGVEEM FLKCTRTIMT KIDSGEVNLE
190 200
HLGVQISSDS GNVTKKPGDS SNCSC