Q54CD6

PR
Gene name
ddx5 (DDB_G0293036)
Protein name
Probable ATP-dependent RNA helicase ddx5
Names
DEAD box protein 5
Species
Dictyostelium discoideum (Slime mold)
KEGG Pathway
ddi:DDB_G0293036
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

619-697 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q54CD6

Entry ID Method Resolution Chain Position Source
AF-Q54CD6-F1 Predicted AlphaFoldDB

No variants for Q54CD6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q54CD6

No associated diseases with Q54CD6

No regional properties for Q54CD6

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q54CD6

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Cytoplasm
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

2 GO annotations of biological process

Name Definition
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins.
rRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNKYKNKYNT DNKFNNSKYI KNNQVELSKQ ELEDEEILKI NDDEFNEGLN KQALFQQDDY
70 80 90 100 110 120
VYKFKKQQKE EKIGGDEKTQ IDNEKPEDFN ITLKSIDFKS INLPSFKKRF LQSSTIKDID
130 140 150 160 170 180
SFEFINSTTE FIIENKSDDD NYYDDDDDDE GDKNKEKEKE KEKEKEKEKE KEKEKEKEKE
190 200 210 220 230 240
KEKEKEKNKE IENKTYPNNC KIPIANTGES ECLPNTLKLF FKKTQFPTPT LFQQYAWPAI
250 260 270 280 290 300
LTGHDIIGTS LPGSGKTLGY LAPMIPHCLA RVDRGGKNKI TGEKAPKQYT GILVLVLVPT
310 320 330 340 350 360
RELGLQVHSN TLIITQLFGI KTSVIYGGIS KNLQIEQLEK EKPQILISTP GRLIEMIENG
370 380 390 400 410 420
HVDLSSVTML VLDEADKMLS KGLIPQLKQI RGQIRPDSQN ILFSATFPDS LKEVSKDWIK
430 440 450 460 470 480
DPSIRLRIGS SELPKLNHIQ QDAQLIAHHK KPRALIKLLS EPQFKEKKKT IVFFNKIKEL
490 500 510 520 530 540
KRISIMLLKS NIKHDTIFGN IDQELREKLI NKFSSSRSTL LLSTDIIGRG IHIDDIFNII
550 560 570 580 590 600
NYDFPRSLEQ YCHRVGRAGR SDKVVNPKAF SFLTNSDSYL VEPFVQFLKD QHQNISIPFL
610 620 630 640 650 660
KLCNENFGTK FEFTLSKRKQ KKLAQKDDVE KDDEAYLAKY EKLIKKDRKK DSDDECKKFK
670 680 690
SFKRKNIDSD SDNDSDSNSD NGKETKSKDK NKKFKKY