Q53609

PR
Gene name
salIM
Protein name
Type II methyltransferase M.SalI
Names
M.SalI, Adenine-specific methyltransferase SalI, Modification methylase SalI
Species
Streptomyces albus G
KEGG Pathway
EC number
2.1.1.72: Methyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

491-563 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q53609

Entry ID Method Resolution Chain Position Source
AF-Q53609-F1 Predicted AlphaFoldDB

No variants for Q53609

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q53609

No associated diseases with Q53609

2 regional properties for Q53609

Type Name Position InterPro Accession
conserved_site DNA methylase, N-6 adenine-specific, conserved site 128 - 134 IPR002052
domain Type II restriction enzyme and methyltransferase RM.Eco57I-like 128 - 236 IPR011639

Functions

Description
EC Number 2.1.1.72 Methyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
acyltransferase activity Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor).
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
site-specific DNA-methyltransferase (adenine-specific) activity Catalysis of the reaction: S-adenosyl-L-methionine + DNA adenine = S-adenosyl-L-homocysteine + DNA 6-methylaminopurine.

1 GO annotations of biological process

Name Definition
DNA restriction-modification system A defense process found in many bacteria and archaea that protects the organism from invading foreign DNA by cleaving it with a restriction endonuclease. The organism's own DNA is protected by methylation of a specific nucleotide, which occurs immediately following replication, in the same target site as the restriction enzyme.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MHSEAREAEA RRLLLQETLD AERTFLERNQ WGQFATPPSL AGEIMRYTID LHEETRINFL
70 80 90 100 110 120
EPSCGSGSFF SALLRNLGDK KIEHAVGVEL DPRFSKAASD LWTGQGLRVI EGDFTSPSLV
130 140 150 160 170 180
SGPVASLLVA NPPYVRHHHL GIDQKRDLVA RCADQLGIKP SGLSGLYLYF VLLSHRLLRA
190 200 210 220 230 240
DAVSTWLIPS EFMDVNYGTA LKEYLATRVQ LVRIHQYDAA EVQFDDALVT SSVVVFRNSP
250 260 270 280 290 300
PRPGHTAEFS FGGTLSEPKV THQIPSAALT PEAKWSRYVT GVMPADINLK QTGPKLSDFF
310 320 330 340 350 360
KIRRGLATGS NAFFIIPRSE AERLGIKRNF LRPILPSPRK LKGDAITADA SGWPDIPEQL
370 380 390 400 410 420
ALLDCPLPIE DLLLENPALA AYLSTADEKI RGGYLVSKRS PWYKQEQREP APILLTYMGR
430 440 450 460 470 480
GKDDQHPLRF IRNDSDAVAT NMYLMLYPTA LLQRYLAGDP ERIKQVHKAL LAITAADLRG
490 500 510 520 530 540
GGRVYGGGLH KMEPKELAAL PADGIATLDP VLREDISMVS VPPRKRTGRP QMPGPSASEV
550 560 570 580
RAWARANGVC VPDRGRLRPE VWDAWRQAHA GEASPLNIDA GDQVALW