Q52KW8
Gene name |
rcc2 |
Protein name |
Protein RCC2 homolog |
Names |
|
Species |
Xenopus laevis (African clawed frog) |
KEGG Pathway |
xla:734455 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q52KW8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q52KW8-F1 | Predicted | AlphaFoldDB |
No variants for Q52KW8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q52KW8 | |||||
No associated diseases with Q52KW8
5 regional properties for Q52KW8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | Regulator of chromosome condensation, RCC1 | 159 - 211 | IPR000408-1 |
| repeat | Regulator of chromosome condensation, RCC1 | 211 - 263 | IPR000408-2 |
| repeat | Regulator of chromosome condensation, RCC1 | 263 - 342 | IPR000408-3 |
| repeat | Regulator of chromosome condensation, RCC1 | 340 - 393 | IPR000408-4 |
| repeat | Regulator of chromosome condensation, RCC1 | 439 - 493 | IPR000408-5 |
Functions
6 GO annotations of cellular component
| Name | Definition |
|---|---|
| chromosome, centromeric region | The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome. |
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| midbody | A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis. |
| nucleolus | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
| spindle | The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| cell cycle | The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. |
| cell division | The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPRKKVTDGS | GPGNGAARPA | NRKKAAASGK | KRSRHEFSSD | EDDLDGSPGS | DGGFQGHNNK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RGPAKGATKA | PTAVIVTEPE | HSKEKIKLEG | SKAKGQLLIF | GATNWDLIGR | KEVPKQQAAY |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RNLGQNLWGP | HRYGCLTGVQ | VRSVASGSCA | AHSLLITVEG | KLWSWGRNDK | GQLGHGDIKR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| IDVPKLIESL | KGEVFVHAAC | GRNHTLALTE | NGSVYAFGEN | KMGQLGLGNK | TDAVPSPAQI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LYNGQPITKV | ACGAEFSMIM | DCKGNLYSFG | CPEYGQLGHN | SDGKYIARAQ | RIEYDCELIA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RRIAIFIEKT | KDGQILPVPN | VVVRDIACGI | NHSLILDSQK | RVFSWGFGGY | GRLGHSEQRD |
| 370 | 380 | 390 | 400 | 410 | 420 |
| EMVPRLVKLF | DFPGRGAAQI | YAGATCSFAV | SEMGGLFFWG | ATNTSRDSTM | YPKAVQDLCG |
| 430 | 440 | 450 | 460 | 470 | 480 |
| WKVRSLACGK | SSIIVAADES | TISWGPSPTF | GELGYGDNKA | KSSTTAQEVK | TLDGIYSDQV |
| 490 | 500 | 510 | |||
| IMGNSHTLVV | ARDETEQDKE | KLKKLPEYNP | RTL |