Q52KP5

PR
Gene name
Nxpe4 (Fam55d)
Protein name
NXPE family member 4
Names
Protein FAM55D
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:244853
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

28-171 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q52KP5

Entry ID Method Resolution Chain Position Source
AF-Q52KP5-F1 Predicted AlphaFoldDB

45 variants for Q52KP5

Variant ID(s) Position Change Description Diseaes Association Provenance
rs3389022945 31 K>M No EVA
rs237952856 33 R>Q No EVA
rs3389041559 35 M>V No EVA
rs3389045448 48 V>L No EVA
rs3389043307 90 L>P No EVA
rs3389045475 97 T>P No EVA
rs218240713 100 T>I No EVA
rs3389030154 104 L>H No EVA
rs3389037301 106 P>H No EVA
rs252989010 115 Q>L No EVA
rs29927469 137 M>L No EVA
rs30136314 142 F>S No EVA
rs3389039189 145 A>G No EVA
rs3389041603 145 A>T No EVA
rs3389041563 150 A>G No EVA
rs51400475 173 T>P No EVA
rs255051714 176 L>M No EVA
rs3400117802 179 L>Q No EVA
rs3389022993 192 R>* No EVA
rs225503151 193 S>A No EVA
rs225503151 193 S>P No EVA
rs225503151 193 S>T No EVA
rs3389009414 196 Q>H No EVA
rs3389023010 197 G>D No EVA
rs3389037391 256 M>I No EVA
rs3389036521 265 Y>C No EVA
rs49121236 285 E>G No EVA
rs3389047117 293 S>P No EVA
rs49039491 294 K>Q No EVA
rs33702650 299 T>A No EVA
rs33732329 312 S>A No EVA
rs3389050029 368 R>M No EVA
rs3388990373 379 Q>* No EVA
rs3389017433 387 D>N No EVA
rs246090665 401 L>F No EVA
rs3389037320 413 E>* No EVA
rs230722550 422 T>I No EVA
rs3388990386 431 V>I No EVA
rs3400038391 435 G>C No EVA
rs30476051 436 Q>H No EVA
rs3400119993 438 F>* No EVA
rs3389017482 438 F>S No EVA
rs3402727863 440 P>L No EVA
rs3389036474 445 L>I No EVA
rs3389017454 459 R>C No EVA

No associated diseases with Q52KP5

No regional properties for Q52KP5

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q52KP5

Functions

Description
EC Number
Subcellular Localization
  • Secreted
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8N323 NXPE1 NXPE family member 1 Homo sapiens (Human) PR
Q969Y0 NXPE3 NXPE family member 3 Homo sapiens (Human) PR
Q5XI89 Nxpe4 NXPE family member 4 Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MKTLASRKSL WMLLFIVIFW VSFTVFRNPV KLRTMFKLPV SFNRWNLVMG PSCPAVPLNL
70 80 90 100 110 120
PVSPKETELR IREVLEKLDK QIPPRPFTHL NYTTSATHST ATILNPRDTH CVGDQLDILV
130 140 150 160 170 180
EARDHLGNRK GYGGDFMRAR MFSPALKAGA SGKVTDFNNG TYLVSFTLFW EGTVSLSILL
190 200 210 220 230 240
MHPSEGVSAL WRSRKQGYDR IIFSGQFVSG ASQVHTECAL VLNSSVELCQ YLDAQDQEAF
250 260 270 280 290 300
YCVKPPNVPC AALTYMQSKN KDVSYLSQQE RSLFERSNIA VEIMEKSNAI SVSKCNTDTA
310 320 330 340 350 360
PVKEKCKLGM VSAIPSGHVW KNAWTPASCS LAPIKMKDCL RGKFIYLMGD STIRQWMEYF
370 380 390 400 410 420
KSKVNTLRSV DLHESGKLQH QLAVDLDEKI SIQWQKHGYP LIGSLVYSVK EIENIARIID
430 440 450 460 470 480
RTGGEKNTVI VISLGQHFRP FPIDLFIRRA LNVHKALQRL LLRSPDTVVV LKTENTRELN
490 500 510 520 530 540
SDVERFSDFH GYTQYLALKD IFQDLNVGVI DAWDMTVAYG INNVHPPEDV VRSQINIFLN
YIC