Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q52DF3

Entry ID Method Resolution Chain Position Source
AF-Q52DF3-F1 Predicted AlphaFoldDB

No variants for Q52DF3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q52DF3

No associated diseases with Q52DF3

10 regional properties for Q52DF3

Type Name Position InterPro Accession
repeat HAT (Half-A-TPR) repeat 52 - 84 IPR003107-1
repeat HAT (Half-A-TPR) repeat 96 - 128 IPR003107-2
repeat HAT (Half-A-TPR) repeat 130 - 164 IPR003107-3
repeat HAT (Half-A-TPR) repeat 280 - 315 IPR003107-4
repeat HAT (Half-A-TPR) repeat 383 - 421 IPR003107-5
repeat HAT (Half-A-TPR) repeat 423 - 459 IPR003107-6
repeat HAT (Half-A-TPR) repeat 547 - 581 IPR003107-7
repeat HAT (Half-A-TPR) repeat 584 - 618 IPR003107-8
repeat HAT (Half-A-TPR) repeat 656 - 690 IPR003107-9
repeat HAT (Half-A-TPR) repeat 692 - 726 IPR003107-10

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
spliceosomal complex Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the spliceosomal splicing of one or more substrate RNAs, and which also contain the RNA substrate(s) from the initial target RNAs of splicing, the splicing intermediate RNA(s), to the final RNA products. During cis-splicing, the initial target RNA is a single, contiguous RNA transcript, whether mRNA, snoRNA, etc., and the released products are a spliced RNA and an excised intron, generally as a lariat structure. During trans-splicing, there are two initial substrate RNAs, the spliced leader RNA and a pre-mRNA.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
mRNA splicing, via spliceosome The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSPAAALTNG SVRQPDLHLV TDDDFVYEQD IQRSPGSTKP WLAYISYKIQ HGTVEEQAFV
70 80 90 100 110 120
LERACMQLPR SYKLWKMYLT FRTKHIAKLN AAIFAAEYRK VNSLFERALI LLNKMPRIWE
130 140 150 160 170 180
MYLKFLMKQP LVTLTRRTFD RALRALPITQ HNRIWALYRP FANSAAGPTA VKIWRRYMQV
190 200 210 220 230 240
HPEDAEDFIE LLYQVGYYTE AAKKYIDVLN NPRFTSKHGK GHFELWSEMV ELLVEHATEV
250 260 270 280 290 300
EAGYETGIDV ERIIRSGIER FADQRGKLWV GLATYWIRRG SFERARDVFE EGITTVMTVR
310 320 330 340 350 360
DFTLVFDSYA EFEESVIGAM MEVAGQRAEK GVVDEAADFD LDIRMMRFEH LMDRRPFLLN
370 380 390 400 410 420
DVLLRQNPNN VNEWEKRVAL WGDNHNEVVN TYTNAIAAVQ PKKASGPFHQ LWANYAKFYE
430 440 450 460 470 480
RGGDLRSARI IMEKAVKVPF KSVVELADMW IEWAEMELRN DNFEEAVRIM AKAVQAPKRS
490 500 510 520 530 540
TVDYFDETLT PQQRVHKSWK LWSFYVDLVE SVGTLEDTKK VYERIFELRI ATPQTVVNYA
550 560 570 580 590 600
NLLEEHKYYE ESFKIYERGL DLFSYPVAFE LWNMYLTKAV DRKISIERLR DLFEQAVEGC
610 620 630 640 650 660
PPKFAKIIYL MYGNLEEERG LARHAMRIYE RATRAVSDED RADMFNFYIT KSASNFGLPS
670 680 690 700 710 720
TRQIYERAIA ALPDDEARDM CLKFADMEKR LGEIDRARAI YGHASQFCDP RTTPAFWTKW
730 740 750 760 770 780
EQFEVQHGNE DTFKEMLRIK RAVQAKYNTD VNFIASQALA RSQQQKQANG HGSGAEDGDD
790 800 810 820 830
GVVDAMEALE RQARAPAGFV AATEGNIKGD AATTNTTVAA NPDAIDIDDM ED