Q52036
Gene name |
bphD |
Protein name |
2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase |
Names |
HOPDA hydrolase, 2,6-dioxo-6-phenylhexa-3-enoate hydrolase |
Species |
Pseudomonas putida (Arthrobacter siderocapsulatus) |
KEGG Pathway |
|
EC number |
3.7.1.8: In ketonic substances |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q52036
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q52036-F1 | Predicted | AlphaFoldDB |
No variants for Q52036
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q52036 | |||||
No associated diseases with Q52036
1 regional properties for Q52036
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Alpha/beta hydrolase fold-1 | 36 - 277 | IPR000073 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.7.1.8 | In ketonic substances |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| 2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity | Catalysis of the reaction: 2,6-dioxo-6-phenylhexa-3-enoate + H2O = benzoate + 2-oxopent-4-enoate. |
| 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity | Catalysis of the reaction: (2E,4Z)-2-hydroxy-6-oxonona-2,4-dienedioate + H2O = (2E)-2-hydroxypenta-2,4-dienoate + H+ + succinate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| aromatic compound catabolic process | The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance containing an aromatic carbon ring. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTALTESSTS | KFLNIKEKGL | SDFKIHYNEA | GNGETVIMLH | GGGPGAGGWS | NYYRNIGPFV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EAGYRVILKD | SPGFNKSDAV | VMDEQRGLVN | ARAVKGLMDA | LGIDRAHLVG | NSMGGATALN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FAIEYPDRIG | KLILMGPGGL | GPSMFAPMPL | EGIKLLFKLY | AEPSYENLKQ | MIQVFLYDQS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LITEELLQGR | WEAIQRQPEH | LKNFLISAQK | APLSTWDVTA | RLGEIKAKTF | ITWGRDDRFV |
| 250 | 260 | 270 | 280 | ||
| PLDHGLKLLW | NIDDARLHVF | SKCGHWAQWE | HADEFNRLAI | DFLRQA |