Q51368

PR
Gene name
tonB (PA5531)
Protein name
Protein TonB
Names
Species
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
KEGG Pathway
pae:PA5531
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-65 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

3 structures for Q51368

Entry ID Method Resolution Chain Position Source
6FIP NMR - A 247-342 PDB
6I97 X-ray 335 A D/E 251-340 PDB
AF-Q51368-F1 Predicted AlphaFoldDB

No variants for Q51368

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q51368

No associated diseases with Q51368

4 regional properties for Q51368

Type Name Position InterPro Accession
domain Protein kinase domain 13 - 271 IPR000719
active_site Serine/threonine-protein kinase, active site 131 - 143 IPR008271
domain Calcium/calmodulin-dependent protein kinase II, association-domain 346 - 473 IPR013543
binding_site Protein kinase, ATP binding site 19 - 42 IPR017441

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Single-pass membrane protein ; Periplasmic side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
outer membrane-bounded periplasmic space The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall.
plasma membrane protein complex Any protein complex that is part of the plasma membrane.

2 GO annotations of molecular function

Name Definition
energy transducer activity The biological transducer activity that accepts energy and converts it to another form, often by transfer to another molecule within the cell.
siderophore transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: siderophore-iron(out) + H+(out) = siderophore-iron(in) + H+(in).

6 GO annotations of biological process

Name Definition
bacterial-type flagellum-dependent swarming motility Bacterial-type flagellum-dependent cell motility in which the action of numerous flagella results in the smooth movement of a group of cells along a solid surface. Swarming motility is observed in groups of bacteria.
cellular response to antibiotic Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
iron import into cell The directed movement of iron ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
single-species biofilm formation A process in which planktonically growing microorganisms of the same species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
type IV pilus-dependent motility Any process involved in the controlled movement of a bacterial cell which is dependent on the presence of type IV pili. Includes social gliding motility and twitching motility.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSPQPSRSPD RFSLAALAED HPTAPAQGDE SESLPCVNAQ RGEPNLRVVD CSGARRDEEV
70 80 90 100 110 120
AVEEVLIPYA HGSDPEDVPG EPPKSRWWLS SGAAVAMHVA IIGALVWVMP TPAELNLGHG
130 140 150 160 170 180
ELPKTMQVNF VQLEKKAEPT PQPPAAAPEP TPPKIEEPKP EPPKPKPVEK PKPKPKPKPK
190 200 210 220 230 240
PVENAIPKAK PKPEPKPKPE PEPSTEASSQ PSPSSAAPPP APTVGQSTPG AQTAPSGSQG
250 260 270 280 290 300
PAGLPSGSLN DSDIKPLRMD PPVYPRMAQA RGIEGRVKVL FTITSDGRID DIQVLESVPS
310 320 330 340
RMFDREVRQA MAKWRFEPRV SGGKIVARQA TKMFFFKIEK RR