Q505L3

PR
Gene name
vps51 (ffr)
Protein name
Vacuolar protein sorting-associated protein 51 homolog
Names
Protein fat-free homolog
Species
Xenopus laevis (African clawed frog)
KEGG Pathway
xla:734484
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-178 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q505L3

Entry ID Method Resolution Chain Position Source
AF-Q505L3-F1 Predicted AlphaFoldDB

No variants for Q505L3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q505L3

No associated diseases with Q505L3

1 regional properties for Q505L3

Type Name Position InterPro Accession
domain Exocyst complex component EXOC2/Sec5, N-terminal domain 45 - 241 IPR039481

Functions

Description
EC Number
Subcellular Localization
  • Golgi apparatus, trans-Golgi network
  • Recycling endosome
  • Localizes to the trans-Golgi network as part of the GARP complex, while it localizes to recycling endosomes as part of the EARP complex
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
EARP complex A quatrefoil tethering complex required for endocytic recycling.
GARP complex A quatrefoil tethering complex required for retrograde traffic from the early endosome back to the late Golgi and biogenesis of cytoplasmic vesicles.
recycling endosome An organelle consisting of a network of tubules that functions in targeting molecules, such as receptors transporters and lipids, to the plasma membrane.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

3 GO annotations of biological process

Name Definition
endocytic recycling The directed movement of membrane-bounded vesicles from endosomes back to the plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins.
lipid transport The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MATVEEEESA KKKKSHGILK LYYGMTEEGK AAERHLEPTD VDGVHFNPEL YLTKLRKESS
70 80 90 100 110 120
LSQLMDVEAD MVRQIRSLDS EMQTLVYENY NKFISATDTI RKMKNDFKKM EDEMDGLASN
130 140 150 160 170 180
MAVITEFSAR ISSTLQVSHQ QITKLSGVHT LLRKLQFLFE LPARLKKCIE LGAYGQAVSY
190 200 210 220 230 240
HSKARSVLHQ YQHMPSFHGI QTDCQAIMAG LADTLRQRFR DPASSPQELS ECVEMLLNLE
250 260 270 280 290 300
EPAHLLCDEF LAHGRGRLAS HLSDLQESGD ILEFVDRGCG GFISDACLLA ASYQSLFSKE
310 320 330 340 350 360
PGNSAQMAEA KLTVFLEELS TGYFELVEKR LHQEKSLGDN SLLVRALDRF HRRLQAPSKL
370 380 390 400 410 420
VPGCGFNRRG TEIVVRAAQE RLAQYLQSLK EFFQGCLTDV RQALAAPRLP GKETSGLGDL
430 440 450 460 470 480
LAGLSASVLN QIKTVLAAVH LFTAKDVAFS NKAYFKGEFC SQGVREGLIV AFITSVCQTA
490 500 510 520 530 540
RQFCEIPGEK GTSTPPSLLL LLSRLCLDYE TSTISYILTL TDEQFLGQDR SPVTPVSSLC
550 560 570 580 590 600
SLARSTAQTL LNQFVKYQGL VVSQMLRKSV ETRDWVTTIE PRNVRAVMKR VVEDITGVDV
610 620 630 640 650 660
QVGLLYEEGA RKAHSSDSSK RTFSVYSSSR LQGRYAQSYT PSAPMDTNLL SNIQKLFSER
670 680 690 700 710 720
IDIFSSVQFN KVSILTGIIK ISLKTFLECV RLRTFGRYGL QQIQVDCHYL QLYLWRFVSD
730 740 750
ENLVHCLLDE VVGSAAHRCL DPAPMEQSVI EVICERG