Q504L8

PR
Gene name
mafb
Protein name
Transcription factor MafB
Names
Maf-B, XMafB
Species
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
KEGG Pathway
xtr:595086
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

140-209 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q504L8

Entry ID Method Resolution Chain Position Source
AF-Q504L8-F1 Predicted AlphaFoldDB

No variants for Q504L8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q504L8

No associated diseases with Q504L8

2 regional properties for Q504L8

Type Name Position InterPro Accession
domain Transcription regulator LuxR, C-terminal 832 - 897 IPR000792
domain MalT-like TPR region 453 - 784 IPR041617

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
DNA-binding transcription factor activity, RNA polymerase II-specific A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II.
RNA polymerase II cis-regulatory region sequence-specific DNA binding Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II.

3 GO annotations of biological process

Name Definition
regulation of DNA-templated transcription Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
regulation of myeloid cell differentiation Any process that modulates the frequency, rate or extent of myeloid cell differentiation.
regulation of transcription by RNA polymerase II Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAGELSIATE LPTSPLAMEY VNDFDLMKFD VKKEPLGGRP DRAIRPCNRL QPTGSVSSTP
70 80 90 100 110 120
ISTPCSSVPS SPSFSPTEQK THMDELYWMT NSYQQVNPEA LNLTPEDAVE ALIGPHQMPP
130 140 150 160 170 180
QMQGYDSFRG HHHHHHNNHH HQNHHQYQGL PHEEMGLPHQ HPHHHHHHHH HQPSPSPSGS
190 200 210 220 230 240
SSSSQQLQNS HQQHQNSSAV EDRFSDDQLV SMSVRELNRH LRGFTKDDVI RLKQKRRTLK
250 260 270 280 290 300
NRGYAQSCRF KRVQQKHHLE NEKTQLIQQV EQLKLEVSRL ARERDAYKIK CEKLANTTFR
310
EAGSTSDNPS SPEFFM