Q503X2

PR
Gene name
mrpl4 (zgc:110034)
Protein name
39S ribosomal protein L4, mitochondrial
Names
L4mt, MRP-L4
Species
Danio rerio (Zebrafish) (Brachydanio rerio)
KEGG Pathway
dre:553771
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-76 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q503X2

Entry ID Method Resolution Chain Position Source
AF-Q503X2-F1 Predicted AlphaFoldDB

No variants for Q503X2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q503X2

No associated diseases with Q503X2

2 regional properties for Q503X2

Type Name Position InterPro Accession
domain Importin-beta, N-terminal domain 28 - 97 IPR001494
domain Exportin-1/Importin-beta-like 100 - 253 IPR013598

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
mitochondrial large ribosomal subunit The larger of the two subunits of a mitochondrial ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).

1 GO annotations of molecular function

Name Definition
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

1 GO annotations of biological process

Name Definition
translation The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q32PI6 MRPL4 39S ribosomal protein L4, mitochondrial Bos taurus (Bovine) PR
Q9BYD3 MRPL4 39S ribosomal protein L4, mitochondrial Homo sapiens (Human) PR
10 20 30 40 50 60
MFRATLAICG RTVVKRQFIS SVSGESALPP NLRLPPNLIG VAAEKRPPPS GSDLPVVRRC
70 80 90 100 110 120
EADVPAHLTP AQTWLESLGS RDSDQLGVVD LHPDVFSVPI RLDILHAVEV WQRNFKRISY
130 140 150 160 170 180
ANVKTRAEVR GGGRKPWQQK RTGRARHGSI RSPLWRGGGI IHGPRGPTSY YYMLPMKVRV
190 200 210 220 230 240
QGLKIALSAK LAQDYLHIVD SLEIPTPDPQ YLQDLVKHRQ WGDSVLIVDV GEEFPQNILK
250 260 270 280 290 300
ATEDLKTVNI IPALGLNVHS LLKHESLVLT LEAVKFLEKK LLWHDVRYTP LYPFKLPYSD
LP