Q4ZN84
Gene name |
lipA |
Protein name |
Lipoyl synthase |
Names |
Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA |
Species |
Pseudomonas syringae pv syringae (strain B728a) |
KEGG Pathway |
psb:Psyr_4358 |
EC number |
2.8.1.8: Sulfurtransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q4ZN84
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q4ZN84-F1 | Predicted | AlphaFoldDB |
No variants for Q4ZN84
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q4ZN84 | |||||
No associated diseases with Q4ZN84
Functions
| Description | ||
|---|---|---|
| EC Number | 2.8.1.8 | Sulfurtransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| 4 iron, 4 sulfur cluster binding | Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. |
| lipoate synthase activity | Catalysis of the reaction: protein N6-(octanoyl)lysine + 2 sulfur + 2 S-adenosyl-L-methionine = protein N6-(lipoyl)lysine + 2 L-methionine + 2 5'-deoxyadenosyl. |
| metal ion binding | Binding to a metal ion. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| protein lipoylation | The lipoylation of peptidyl-lysine to form peptidyl-N6-lipoyl-L-lysine. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTDTVQTLIP | TLDVSERVAR | PKVEAGVKLR | GAEKVARIPV | KIIPTVDLPK | KPDWIRVRIP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VSPEVDRIKQ | LLRKHKLHSV | CEEASCPNLG | ECFSGGTATF | MIMGDICTRR | CPFCDVGHGR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PKPLDVNEPK | SLAIAIADLR | LKYVVITSVD | RDDLRDGGAQ | HFADCIREIR | LLSPGVQLET |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LVPDYRGRMD | VALEITAAEP | PDVFNHNLET | VPRLYKAARP | GSDYQWSLTL | LQRFKQMVPH |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VPTKSGLMLG | LGETDEEVIE | VMQRMREHDI | DMLTLGQYLQ | PSRNHLPVQR | FVHPDTFAWF |
| 310 | 320 | 330 | |||
| AEEGYKMGFK | NVASGPLVRS | SYHADEQAKI | AKAML |