Q4X1X0

PR
Gene name
mrh4 (AFUA_2G08480)
Protein name
ATP-dependent RNA helicase mrh4, mitochondrial
Names
Species
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
KEGG Pathway
afm:AFUA_2G08480
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

5-133 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q4X1X0

Entry ID Method Resolution Chain Position Source
AF-Q4X1X0-F1 Predicted AlphaFoldDB

No variants for Q4X1X0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4X1X0

No associated diseases with Q4X1X0

2 regional properties for Q4X1X0

Type Name Position InterPro Accession
conserved_site Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site 69 - 81 IPR018480-1
conserved_site Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site 189 - 200 IPR018480-2

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Mitochondrion
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

1 GO annotations of biological process

Name Definition
rRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNRLGRLPLP LPPSVCLFCR FRATASLPSS LQATRSMATA RLRRRVARMT LSPDVAKPSV
70 80 90 100 110 120
VKKTRGDKER FGPFAGMNQT EARIRETPRA RSRAAQKRSG EPEEDSQKES PLYKALKMQT
130 140 150 160 170 180
ALTPIPYGRR AAIKAKIADI TSFDQFQLLP VVRNSISSQA LPGLVDVTPT PIQRLAIPRL
190 200 210 220 230 240
LEEPKTEKKP TKADDDEPRY DQYLLAAETG SGKTLAYLLP VVDAVKREEA RDKELEKKEQ
250 260 270 280 290 300
EEKAREREER LKNRAFDIEP EIPPLSNAGR PRAIILVPTS ELVAQVGVKV KALSHTVKYR
310 320 330 340 350 360
SGMISSNFTP RRIKNTLFHP DGIDILVATP HLLASIAKTE PYVLSRVSHL VLDEADSLLD
370 380 390 400 410 420
RSFAPTTTEI ISKAAPSLRK LILCSATIPR SLDNLLRKRY PDIKRLTTPN LHAIPRRVQL
430 440 450 460 470 480
GVVDIEKDPY RGNRSLACAD VIWSIGKAGD AESEGPYASY VAPKTKKILV FVNEREEADE
490 500 510 520 530 540
VAQFLRSKGI DAQSLSRDSD ARKQEEILAE FTEAPPPPSP DEILLAQKKR RYEDAIPFEM
550 560 570 580 590 600
PEKANQGSSR RLANTKVLVT TDLASRGIDT LAVKTVILYH VPHTTIDFIH RLGRLGRMGK
610 620 630
RGRGVVLVGK KDRKDVVKEV REGMFRGQAL I