Q4WZY1

PR
Gene name
atg22-2 (AFUA_2G15370)
Protein name
Autophagy-related protein 22-2
Names
Species
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
KEGG Pathway
afm:AFUA_2G15370
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-131 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q4WZY1

Entry ID Method Resolution Chain Position Source
AF-Q4WZY1-F1 Predicted AlphaFoldDB

No variants for Q4WZY1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4WZY1

No associated diseases with Q4WZY1

No regional properties for Q4WZY1

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q4WZY1

Functions

Description
EC Number
Subcellular Localization
  • Vacuole membrane ; Multi-pass membrane protein
  • Vacuole and punctate structures
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
vacuolar membrane The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
amino acid transmembrane export from vacuole The directed movement of amino acids out of the vacuole, across the vacuolar membrane.
autophagy The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAFNSTPPVS PGGEAQQRPP RFPGEDTTPT SQKEIWGWYA YGIAAEVFAV CGVGSFLPLT
70 80 90 100 110 120
LEQLAREHGT LLSSHLPCVR FSSPSTAPGN GTTTATFRRD GTDNDQCVVS VLGLQVNTAS
130 140 150 160 170 180
FAMYTFSLAV LVQALTLISF SALADYENNR KTLLLAFGFI GSMTSMLFIF IAPPVYILAS
190 200 210 220 230 240
LLVVVGVTCL GSSFVVLNSF LPVLVANDPS IQTAHKEQGE ELSPVNSNGE FVRFEDLDEE
250 260 270 280 290 300
ISRDSDDHFT TGHRPKTKAA GSASPELQLS TRISSKGVGL GYCAAVLVQI LSILMLFALS
310 320 330 340 350 360
KTSLPKISGT LPLRFVLLLV GIWWFSFTMV SRRWLRDRPG PPLASSKGAA RNSRWRIWLR
370 380 390 400 410 420
LIGFAWKSLW KTAKVAVKLR EVIIFLIAWF LLSDAMATVS GTAILFARTE LKMSTTAVGL
430 440 450 460 470 480
LSITATLSGM AGAFLWPVVS RRLRLKSNHT IMLCIALFEV IPLYGMLAYI PLFKKWGVVG
490 500 510 520 530 540
LQQPWEIFPL GIVHGLVSGG LSSYCRSFFG LLIPPGSEAA FYALYAATDK GSSFIGPAIV
550 560 570 580 590 600
GMLIDATGQV RSGFFFIAVL ILLPIPLIWM VNAEKGRQDG LAMADILEKS HREHASEYGG
610
PSEEAEGLLA RDI