Q4WZJ2

PR
Gene name
atp25 (AFUA_2G16740)
Protein name
ATPase synthesis protein 25, mitochondrial
Names
Species
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
KEGG Pathway
afm:AFUA_2G16740
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-131 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q4WZJ2

Entry ID Method Resolution Chain Position Source
AF-Q4WZJ2-F1 Predicted AlphaFoldDB

No variants for Q4WZJ2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4WZJ2

No associated diseases with Q4WZJ2

5 regional properties for Q4WZJ2

Type Name Position InterPro Accession
domain ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain 152 - 375 IPR000194
domain ATP synthase, alpha subunit, C-terminal 382 - 511 IPR000793
domain ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain 29 - 95 IPR004100
active_site ATPase, alpha/beta subunit, nucleotide-binding domain, active site 366 - 375 IPR020003
domain ATP synthase, F1 complex, alpha subunit nucleotide-binding domain 97 - 378 IPR033732

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
mitochondrial inner membrane The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

3 GO annotations of biological process

Name Definition
mitochondrial gene expression The process in which a mitochondrial gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
mitochondrial proton-transporting ATP synthase complex assembly The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the mitochondrial inner membrane.
mRNA stabilization Prevention of degradation of mRNA molecules. In the absence of compensating changes in other processes, the slowing of mRNA degradation can result in an overall increase in the population of active mRNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNRVLSKGPK GLNGLLRACP SNSGRSFLYH STYNVSSRTF WSASRLRSED SPSGSQPLKP
70 80 90 100 110 120
DPNDGIGNNT SSASSQHTPW YLQEEALIEE PRQISSRDQI PELPENSPAI LPVLLDYIFK
130 140 150 160 170 180
DLGLDELRSI DLRGLETPPP IGANSIMIIG TARSVKHLNV SADRLCRWLR STYKLTPYAD
190 200 210 220 230 240
GLLGRNELKI KLRRKARRAR VASRAGTTVD EKDDGITTGW ICVNAGVVEN SPVGEQASRK
250 260 270 280 290 300
VEGFGNIVGG TRVVVQMFTE EKRAEVDLEG LWLATIERDR RQKQVSIDTK SDAPHEEVRA
310 320 330 340 350 360
PTPVQNSSSD HVFGPHCRSS TILPLEQRRG LHSKCRLLGP ETEHNQEDGL DDGLDDGLDM
370 380 390 400 410 420
SPDSISTPTD QLAANRTCDK EVDTDSLLEH LSGLPDEQVL SELGAGQEDR DSTPFLRRFY
430 440 450 460 470 480
DALSQMSTEE AAVARVKLLC TAISRHHQGY SKESLWKAFM TCNYHTYPIS DELGFEIVSA
490 500 510 520 530 540
LLTALPPHQK GPKATGVLPE ADRELALRVL EHLSLRGTDV LNMKVFHLLY EAASHPTSFS
550 560 570 580 590 600
GEEVIKDVTD ATKDRPTSRV AKMIESLDIQ FDPEDARKLM MSMFRNGDYD GFWNLWHKLP
610 620 630 640 650 660
LYGSPRTSAD YEMLFRLHAD LRDECRARDC VSTWVPMMSR EHPPIPLRGQ VVQDIMHCLL
670 680 690 700
IGEPAIDRMA RAGSTSNLVL IWNDCKNIAL GRGRRGSVER MNVV