Q4WVK2
Gene name |
ncs2 (ctu2, AFUA_5G12400) |
Protein name |
Cytoplasmic tRNA 2-thiolation protein 2 |
Names |
|
Species |
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus) |
KEGG Pathway |
afm:AFUA_5G12400 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q4WVK2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q4WVK2-F1 | Predicted | AlphaFoldDB |
No variants for Q4WVK2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q4WVK2 | |||||
No associated diseases with Q4WVK2
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| nucleotidyltransferase activity | Catalysis of the transfer of a nucleotidyl group to a reactant. |
| sulfurtransferase activity | Catalysis of the transfer of sulfur atoms from one compound (donor) to another (acceptor). |
| tRNA binding | Binding to a transfer RNA. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| protein urmylation | Covalent attachment of the ubiquitin-like protein URM1 to another protein. |
| tRNA thio-modification | The addition a sulfur atom to a nucleotide in a tRNA molecule. |
| tRNA wobble position uridine thiolation | The process in which a uridine residue at position 34 in the anticodon of a tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps. |
| tRNA wobble uridine modification | The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MQVCWFERFG | GGNQLLTVLS | SSRTCYARFV | NFKVFKRMEN | YRLRRNMPRT | GPCKLLLPLS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| CGISSSVLLH | ILNAQIQHEL | AKSHPSPGFD | LHLLVIEPSS | ISHSSLSYDE | GFELLQQTFP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LHSFTRIPLH | SIFELDPELQ | EVISQFSKDG | FVDDTGLSAK | ERLDAFRASI | PTSTSKVDVD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| YILITRLVVA | FAKKIACRGV | LWGDTDTRLA | AKTLANVAKG | RGSSLTWQVC | DGMSPFGVEF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| NFPLRDLFKA | EVDNYASFFP | ELTRIIIPDE | PPSENVLTKN | LSIDELMMRY | VQTQGEKYPG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VMANVTRTAS | KLQASLMPAN | VPQCSFCGAF | MLNSGNNDGG | DTTGASRALE | LCYACIRSRP |
| ELTC |