Q4WTH1

PR
Gene name
utp25 (AFUA_1G09320)
Protein name
U3 small nucleolar RNA-associated protein 25
Names
U3 snoRNA-associated protein 25, U three protein 25
Species
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
KEGG Pathway
afm:AFUA_1G09320
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-108 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q4WTH1

Entry ID Method Resolution Chain Position Source
AF-Q4WTH1-F1 Predicted AlphaFoldDB

No variants for Q4WTH1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4WTH1

No associated diseases with Q4WTH1

No regional properties for Q4WTH1

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q4WTH1

Functions

Description
EC Number
Subcellular Localization
  • Nucleus, nucleolus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
small-subunit processome A large ribonucleoprotein complex that is an early preribosomal complex. In S. cerevisiae, it has a size of 80S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins.

2 GO annotations of molecular function

Name Definition
rRNA binding Binding to a ribosomal RNA.
U3 snoRNA binding Binding to a U3 small nucleolar RNA.

1 GO annotations of biological process

Name Definition
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDHETQMDDV LSDSDDDEDQ QTARPYNELI QLLQVNTEPK GPARKRRKVE YNGGEKRDFV
70 80 90 100 110 120
PAANGEEVDA ALQGDDDLQE QEPSDEEEED HPEEADGNHG SDDEEDANDP FETHFSAIDE
130 140 150 160 170 180
NKLALKIKSA EEKKWKNAKK EISSGLKLVR AIPDVGEGDV SLLPAMKHFS SVKLKKKLCG
190 200 210 220 230 240
PATERIPEIS GDAQHIAPYI FNYQDVLYGA RTTSNSSAMR DILAVHAVNH ILKTRDRVLK
250 260 270 280 290 300
NNSRIAKEQD ADLDLRDQGF TRPKVLYLLP TRQACVRAVE SITRFFQPEQ QENKKRFLDS
310 320 330 340 350 360
FSAADDKSWE NKPEDFRELF GGNDDDMFRL GLKFTRKTMK YFSQFYNSDI ILASPLGLRT
370 380 390 400 410 420
IMDQADVKKR DHDFLSSVEL VIVDHADALL MQNWDHVGYI LDRLNLQPKE AHGCDFSRVR
430 440 450 460 470 480
TWYLDNHARF VRQMIVSASF ITPEINSLFS THMQNFAGKV KVTPVYVGAI SEVPLPVSVK
490 500 510 520 530 540
QTFSRFDSLT PTKDPDARFK HFTTTVLSSL VRNITSSRDK SSAGGTLIFI PSYLDFVRVR
550 560 570 580 590 600
NYFATSSQTT NVSFGAISEY SEVREMTRAR THFMNGRHAV LLYTERLHHF RRYQLRGVKR
610 620 630 640 650 660
IVMYGVPENP LFWGEIVGFL GLDPAGVVDA AEGGVRALFS KWDALKLERI VGTKRVGNML
670
REKGGDTFTF V