Q4WPF8

PR
Gene name
ccp1 (AFUA_4G09110)
Protein name
Cytochrome c peroxidase, mitochondrial
Names
CCP
Species
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
KEGG Pathway
afm:AFUA_4G09110
EC number
1.11.1.5: Peroxidases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-85 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q4WPF8

Entry ID Method Resolution Chain Position Source
AF-Q4WPF8-F1 Predicted AlphaFoldDB

No variants for Q4WPF8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4WPF8

No associated diseases with Q4WPF8

3 regional properties for Q4WPF8

Type Name Position InterPro Accession
domain Polymerase, nucleotidyl transferase domain 51 - 147 IPR002934
domain 2-5OAS/ClassI-CCAase, nucleotidyltransferase domain 49 - 155 IPR006116
domain tRNA nucleotidyltransferase, substrate binding 161 - 271 IPR015329

Functions

Description
EC Number 1.11.1.5 Peroxidases
Subcellular Localization
  • Mitochondrion matrix
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
mitochondrial matrix The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.

4 GO annotations of molecular function

Name Definition
cytochrome-c peroxidase activity Catalysis of the reaction: 2 ferrocytochrome c + hydrogen peroxide = 2 ferricytochrome c + 2 H2O.
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
metal ion binding Binding to a metal ion.
peroxidase activity Catalysis of the reaction: a donor + a peroxide = an oxidized donor + 2 H2O.

3 GO annotations of biological process

Name Definition
cellular response to oxidative stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
hydrogen peroxide catabolic process The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2).
response to reactive oxygen species Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MASAARSASR AFLRSTPTTS SFRPAVRAAR FALPAQGFRA AGRRGYASEA NSGKSSSNVF
70 80 90 100 110 120
LWAGLAVAGG AGAYLYLNGS DSVTSKTFVP GKEDYQKVYD AIARRLADET DYDDGSYGPV
130 140 150 160 170 180
LVRLAWHASG TYDKETGTGG SNGATMRFAP ESDHGANAGL KIARDFLEPI KAQFPWISYS
190 200 210 220 230 240
DLWTLAGACA IQELGGPTIP WRPGRQDKDV AACTPDGRLP DASKDQRHIR DIFYRMGFND
250 260 270 280 290 300
QEIVALIGAH ALGRAHPDRS GYDGPWDFSP TVFTNEFFRL LVDEKWQNRK WNGPAQFTDK
310 320 330 340 350 360
TTKTLMMLPA DLALIKDKEF KKHVERYARD SDAFFKDFSD AFVKLLELGV PFTSKAEDRY
VFKTSE