Q4WKB9

PR
Gene name
cwc22 (AFUA_1G03010)
Protein name
Pre-mRNA-splicing factor cwc22
Names
Species
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
KEGG Pathway
afm:AFUA_1G03010
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

4-106 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q4WKB9

Entry ID Method Resolution Chain Position Source
AF-Q4WKB9-F1 Predicted AlphaFoldDB

No variants for Q4WKB9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4WKB9

No associated diseases with Q4WKB9

No regional properties for Q4WKB9

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q4WKB9

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
catalytic step 2 spliceosome A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs.
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
U2-type spliceosomal complex Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron that has canonical consensus sequences near the 5' and 3' ends.

1 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.

1 GO annotations of biological process

Name Definition
mRNA splicing, via spliceosome The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTDSVVLQSA VRVPTPPPGT SYSPQPSVSR KRSPPSRSPS PRRRRSPPGD SLKENGDAPR
70 80 90 100 110 120
IDPERAVERE RQLAERLRQH EKREAARKPM TEEEKQAAAK AEYEKLLNMR SGGTYIPPAR
130 140 150 160 170 180
LRALQAQITD KNSKEYQRMA WEALKKSING LINKVNVSNI KFIVPELFGE NLVRGRGLFC
190 200 210 220 230 240
RSIMKAQAAS LPFTPIYAAM AAIVNTKLPQ VGELLLNRLI VQFRKAFKRN DKAVCISSTT
250 260 270 280 290 300
FIAHLCNQQV AHEMLAAQIL LLLLHKPTDD SVEIAVGLTR EVGQHLEEMS PPIALAVFDQ
310 320 330 340 350 360
FRNILHEADI DKRVQYMIEV LFQVRKDRYK DNPAIKDELD LVEEEDQITH RIGLDDEIDT
370 380 390 400 410 420
QDGLNVFKYD PQWEEHEEAY KKLKAEILGE GSDDDEEDED ETDESSDEEE EERQMEIKDQ
430 440 450 460 470 480
SNTDLVNLRR TIYLTIMSSI DFEECCHKLM KISLPPGLEP ELPSMIIECC SQERTYSKFY
490 500 510 520 530 540
GLIGERFAKI NRLWSDLFEA AFAKYYDTIH RYETNRLRNI ARFFGHMLST DAIGWHVMSV
550 560 570 580 590 600
IHLNEDETTS SSRIFIKILF QDLGEHLGLA KLQERMRDEI LRPSFEGLFP LDNPRNTRFS
610 620 630 640 650 660
INYFTSIGFG ILTEDMREHL KNLPKPTVPA LPARDAESDS ESVSSHSTCS TCTGSSRSRS
670 680 690 700 710 720
RSYSYSRSPS RSRGRRRSIS RGRSYSRSVS GSSRGRSYTP SYSRSRSPVP KSRRRSVSYS
730 740 750 760 770 780
RSRSPAGRRR SSVSRTPPRR VRGKSYDSRS PSRSVTPPRR RTSYSRRDRS YSRSLSRSVT
790 800 810 820 830 840
PPLRAVDARA RGRRYSSQSL SPPRRRAERS VSPQRPPPGR RPRGDSLSRS PSPPPRYARE
850 860 870 880
QRRRRNSSSA SASRSPPHRD SNRRRSLSRT PPRRGRASDY L