Q4WID9
Gene name |
grc3 (AFUA_2G02190) |
Protein name |
Polynucleotide 5'-hydroxyl-kinase grc3 |
Names |
|
Species |
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus) |
KEGG Pathway |
afm:AFUA_2G02190 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q4WID9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q4WID9-F1 | Predicted | AlphaFoldDB |
No variants for Q4WID9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q4WID9 | |||||
No associated diseases with Q4WID9
1 regional properties for Q4WID9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain | 338 - 540 | IPR032319 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleolus | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| polynucleotide 5'-hydroxyl-kinase activity | Catalysis of the reaction: NTP + 5'-dephosphopolynucleotide = NDP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | Endonucleolytic cleavage within ITS2 between the 5.8S rRNA and the LSU-rRNA of an rRNA molecule originally produced as a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. |
| phosphorylation | The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. |
| RNA processing | Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules. |
| rRNA processing | Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKRKAEKQQA | TAPVSAFAAR | KARQQQARLL | EPEKTAQNEP | AVEPPSKRAR | RSPEEGAARQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AANENDRVQT | RRSARTKAET | LSSAELAEKQ | PQESAAAARA | QTAERTPPPE | KGDADTFDAA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EEEEEEEKEE | DILERENGVG | VIAVEDDAEG | YESPADDVPQ | VQNFPLSKTR | LNKSNIVSSD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ERTLCVRIKE | KMTLVLLGHY | DLWVKRGVIS | LMGAKLHPSP | RLYRVYAPST | HSLPVIKCVA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GVDGESEIEV | KSCNSGIYRL | RHLSPLYQRI | WNGKHTAADK | LTLKKVSAST | KRTFSVLYTS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SDDSWNRHLR | PLHLEKQWSS | AIRSLSQRGG | RLKVLICGPK | ASGKSTFSRY | LLNHLLSPAP |
| 370 | 380 | 390 | 400 | 410 | 420 |
| QTENNHRNTD | GVAFLDLDPG | QPEFCPMGQV | YLAHLRSPFF | GPPFTHPSLA | ESQDGSIIRS |
| 430 | 440 | 450 | 460 | 470 | 480 |
| HHIGAISPKE | DPDHYVLAAM | DLMDRYRALL | ASYPQCPLII | NYPGWIFGLG | LEVATWLVKS |
| 490 | 500 | 510 | 520 | 530 | 540 |
| LGLSDVVYMS | EKGPAEVVEP | LGHAAQEARV | PLTTLPSQPT | DFVSRSSAQL | RSMQVQSYFH |
| 550 | 560 | 570 | 580 | 590 | 600 |
| MSHPSEIHNP | QWLDTTMSRT | RPLVVDYAGP | RQGIRGIMVM | GSQISPNLLH | EALDGALVGV |
| 610 | 620 | 630 | 640 | 650 | 660 |
| VAVESPNAIM | GQADAAGFSG | SSHGDATQGA | EDLSSAASDI | DMNDVTDACH | GDVAPTSSSS |
| 670 | 680 | 690 | 700 | 710 | 720 |
| FESMIIRTPN | EDLPYLFVGS | GSCNPLDPKA | SNCLGLALVR | SIDVPSRKLE | LITPIPASKL |
| 730 | 740 | 750 | 760 | 770 | 780 |
| RDALEQGHGI | VLVRGMLDNP | SWAISEDYYA | ARAAERRHQE | LVAKARKETN | TRDGQDAAVD |
| 790 | 800 | 810 | 820 | 830 | 840 |
| ADTQGMVSAL | LKDRIRRASN | VPWMTVIEDN | SRRHREAAQR | KKSLWKLRKK | AYPGSESETD |
| W |