Q4WEU2

PR
Gene name
rpc82 (rpc3, AFUA_5G04200)
Protein name
DNA-directed RNA polymerase III subunit rpc3
Names
RNA polymerase III subunit C3
Species
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
KEGG Pathway
afm:AFUA_5G04200
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

106-299 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q4WEU2

Entry ID Method Resolution Chain Position Source
AF-Q4WEU2-F1 Predicted AlphaFoldDB

No variants for Q4WEU2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4WEU2

No associated diseases with Q4WEU2

2 regional properties for Q4WEU2

Type Name Position InterPro Accession
domain RNA polymerase III Rpc82, C -terminal 320 - 462 IPR008806
domain RNA polymerase III subunit RPC82-related, helix-turn-helix 8 - 64 IPR013197

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
RNA polymerase III complex RNA polymerase III, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces 5S rRNA, tRNAs and some of the small nuclear RNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase I and others of which are also found in RNA polymerases I and II. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.

1 GO annotations of molecular function

Name Definition
single-stranded DNA binding Binding to single-stranded DNA.

1 GO annotations of biological process

Name Definition
DNA-templated transcription The synthesis of an RNA transcript from a DNA template.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTSQFAAELC ELLVEENFGE LFGRIFATLS RYDRLNLPRL KAYSELPNRQ LLPALAAMIQ
70 80 90 100 110 120
QHLVYHYTSY DDGVTYYEAN MQSAYYLVRS GKILEFVEER LGKYAATVLS TIMYLGHAQV
130 140 150 160 170 180
SYLETLPELT SEAVKANGVP EEHGEHEEDE EQSNGLNGEH SNEQPELLHP TLKALAAHGY
190 200 210 220 230 240
IIRVREAQFQ SHADNILDAE RAIRSKPEMK ALKGKRLEEA VIEGTLGLLK ERTDGDLTRG
250 260 270 280 290 300
LIVHGVPRGA KRKHSSRRAD EPNKKCRTDF ASVDENDEHD EEEENEWSDD EMGYDTTPME
310 320 330 340 350 360
VSARELYATV SERETEQGVS PATAKVYECL LRRIEYQTHQ CRDTAEIPRE GEEGEQYSVP
370 380 390 400 410 420
IALSALAEDV NPQLDLSSST GPMDSSQPDG RRGKRPWDGD VEGTNHEEAN GLSSGGSGGN
430 440 450 460 470 480
RTFEIDQHLS LLAQPPHNLT SKRMVSGLIT WTVEFRHLAR KLRHLELERM IEARYGDVAL
490 500 510 520 530 540
RVVRVLHAKG KLDEKRLQEI SLLPFKDLRQ VLASMQAGGF VDLQEVPRDA QRQPSRTIYL
550 560 570 580 590 600
WYYDPDRICN SVLQDTYKAM SRCLQRLRFE RSRIKDFLEK TERSDVKGNE QRFLSEPELV
610 620
LLEQWRAKEA LLLGEVARLD EMVAVMRDY