Q4WEP0

PR
Gene name
sfh5 (AFUA_5G03690)
Protein name
Phosphatidylinositol transfer protein sfh5
Names
PITP sfh5
Species
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
KEGG Pathway
afm:AFUA_5G03690
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-218 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q4WEP0

Entry ID Method Resolution Chain Position Source
AF-Q4WEP0-F1 Predicted AlphaFoldDB

No variants for Q4WEP0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4WEP0

No associated diseases with Q4WEP0

2 regional properties for Q4WEP0

Type Name Position InterPro Accession
domain CRAL-TRIO lipid binding domain 183 - 363 IPR001251
domain CRAL/TRIO, N-terminal domain 108 - 165 IPR011074

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Endoplasmic reticulum membrane ; Peripheral membrane protein
  • Microsome membrane ; Peripheral membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
cortical endoplasmic reticulum A cortical network of highly dynamic tubules that are juxtaposed to the plasma membrane and undergo ring closure and tubule-branching movements.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
phosphatidylinositol transfer activity Removes phosphatidylinositol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.

2 GO annotations of biological process

Name Definition
Golgi to plasma membrane protein transport The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane.
regulation of exocytosis Any process that modulates the frequency, rate or extent of exocytosis.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSVTMADQQP EKTTAPASDV ADSQPAVVSN TDTRKETTET AEPQSEDKTA TTTAQPAVET
70 80 90 100 110 120
TATQSGTAET PAEADKAPAE VQQPPQAEEE KPVAQQPEQP AYLAKNPALS QFFERLPAIV
130 140 150 160 170 180
SSSGHAEMWG VPLKDSNDAP TVNVLIKFLR ANEGNVKLAE EQLTKALKWR KETNPSALAE
190 200 210 220 230 240
STSYSATKFG GLGYLTTYKE ANGAETVVTW NIYGGVKDIN TTFGDMNEFV KWRVALMELA
250 260 270 280 290 300
VKELKMAEAT SVIDYDGEDP YQMIQVHDYQ NVSFLRLNPA IKAATKKTIE VFTTAYPELL
310 320 330 340 350 360
REKFFVNVPA IMGWMFAAMK VFLSKNTTRK FHPISNGANL AREFPSLKDQ FPKVYGGSAP
370 380 390 400 410 420
ALQEGARTVS LIQDESAPAA TEQSKEQANK EEAAQEESKP ESAPEQPKAD PDVIVQEAPA
ADAK