Q4WDF1

PR
Gene name
epl1 (AFUA_6G04530)
Protein name
Enhancer of polycomb-like protein 1
Names
Species
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
KEGG Pathway
afm:AFUA_6G04530
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-76 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q4WDF1

Entry ID Method Resolution Chain Position Source
AF-Q4WDF1-F1 Predicted AlphaFoldDB

No variants for Q4WDF1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4WDF1

No associated diseases with Q4WDF1

1 regional properties for Q4WDF1

Type Name Position InterPro Accession
domain Enhancer of polycomb-like, N-terminal 6 - 146 IPR019542

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
Piccolo NuA4 histone acetyltransferase complex A heterotrimeric H4/H2A histone acetyltransferase complex with a substrate preference of chromatin over free histones. It contains a subset of the proteins found in the larger NuA4 histone acetyltransferase complex; for example, the S. cerevisiae complex contains Esa1p, Yng2p, and Epl1p.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

3 GO annotations of biological process

Name Definition
cell cycle The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
DNA repair The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
regulation of transcription by RNA polymerase II Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGRTRPKKLT SKASIPIVRE HEIDIIDDEV QNALQQVETG VEKAEESEFH LQAAISATAQ
70 80 90 100 110 120
GKVNEAHIPT PETVLSNLRY DELYPPIFSQ PATYIRFSST IEDCCGCPYN MTEEDDVFFK
130 140 150 160 170 180
IMNEKREPSN RITEDQFEEV MYFFEETAQT KQPFAAVDSP PVLSFAEMQD SMDATVEESV
190 200 210 220 230 240
KCFAKDIYEH WKLRRIATGN RPLLPSLKFE TGQDTDDTDP YVCFRRREVR QIRKTRGRDA
250 260 270 280 290 300
QSADKLRRLR KELEDARQLV ALVRQRELAR KEMLSMERQI FLQRSEVKEM KRKLNIKDDD
310 320 330 340 350 360
EDLINQKVTS IPARLPHAFA NLPEQPKKKP AEAPAAQRPT APQIRMPQKP GTQAADDMQL
370 380 390 400 410 420
LEDVQAEKEN EILRDIKQNI AKHIKWNEGY VDYTRAPLSP PPEKTFQAAF RPAITTQLPT
430 440 450 460 470 480
PPSSDSSDNM MLESALDTAN SLSFRDKLVP RTWEMNEDTC RIPSFRRRIG RGGRLMIDRR
490 500 510 520 530 540
NMASRCRIEM DPLKADRFKY DREDSDDESE FECDPYDVQI MQHRAIMAAK ARDQAAAAAQ
550 560 570 580
AHAQAQAQKR LQAEQTTTNN GPPNIGHTMG SNPGPGAVAS TS