Q4WDD0

PR
Gene name
cwc21 (AFUA_6G04320)
Protein name
Pre-mRNA-splicing factor cwc21
Names
Species
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
KEGG Pathway
afm:AFUA_6G04320
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

5-83 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q4WDD0

Entry ID Method Resolution Chain Position Source
AF-Q4WDD0-F1 Predicted AlphaFoldDB

No variants for Q4WDD0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4WDD0

No associated diseases with Q4WDD0

4 regional properties for Q4WDD0

Type Name Position InterPro Accession
conserved_site Actinin-type actin-binding domain, conserved site 10 - 19 IPR001589
domain Calponin homology domain 8 - 115 IPR001715-1
domain Calponin homology domain 124 - 229 IPR001715-2
domain Cortexillin, coiled coil 231 - 337 IPR015383

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
spliceosomal complex Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the spliceosomal splicing of one or more substrate RNAs, and which also contain the RNA substrate(s) from the initial target RNAs of splicing, the splicing intermediate RNA(s), to the final RNA products. During cis-splicing, the initial target RNA is a single, contiguous RNA transcript, whether mRNA, snoRNA, etc., and the released products are a spliced RNA and an excised intron, generally as a lariat structure. During trans-splicing, there are two initial substrate RNAs, the spliced leader RNA and a pre-mRNA.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
mRNA processing Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
RNA splicing The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSSNVGLSTP RGSGTSGYVQ RNYAFMKPRN AGYGAPYPPV SGANANDSSR GFKQRQPDKQ
70 80 90 100 110 120
ILEHDRRRAV EVKVMEERER LEEENERIEQ EGKGKGEGEG KVLSEEEIEE RCEALRARLL
130 140 150 160 170 180
KEMEEEENRK GDAADGERDE GRERRGWKRG PRDRERDLPP RERRQFKTYQ VHELAEAKIE
190 200 210
ESERFKKALG IREDTETGEI SSGRKDYEPR KRDRERY