Q4VT38
Gene name |
gpa-14 (CBG04031) |
Protein name |
Guanine nucleotide-binding protein alpha-14 subunit |
Names |
|
Species |
Caenorhabditis briggsae |
KEGG Pathway |
cbr:CBG_04031 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q4VT38
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q4VT38-F1 | Predicted | AlphaFoldDB |
No variants for Q4VT38
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q4VT38 | |||||
No associated diseases with Q4VT38
No regional properties for Q4VT38
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q4VT38 | |||
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| heterotrimeric G-protein complex | Any of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer; extrinsic plasma membrane proteins (cytoplasmic face) that function as a complex to transduce signals from G protein-coupled receptors to an effector protein. |
5 GO annotations of molecular function
| Name | Definition |
|---|---|
| G protein-coupled receptor binding | Binding to a G protein-coupled receptor. |
| G-protein beta/gamma-subunit complex binding | Binding to a complex of G-protein beta/gamma subunits. |
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
| metal ion binding | Binding to a metal ion. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| adenylate cyclase-modulating G protein-coupled receptor signaling pathway | A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation or inhibition of adenylyl cyclase activity and a subsequent change in the intracellular concentration of cyclic AMP (cAMP). |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MFSCFNNLGL | DYCYQCMHGP | EGCMVPSRQG | DGGELYAHSE | ELEAKLRGLA | KKESLEIEKS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LENDKKTYGS | HIKILILGGP | SSGKSTIFKQ | MQIIHSNGFK | TEQELIQYRG | LIDTNIRQTY |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RQLVSGARVV | GISLESLESL | VHDINKVYAP | MAADEFSIRT | IPDVVEPLTA | FWNSREIQEV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| YKRRYEFELL | DSTKYYLENL | NRISKSDYLP | NEEDIVHSRK | ATVSINSIVF | QYTGVSLLMV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| DVGGQRSERK | KWLHLFDDAK | VVIFVIDLTG | YAKKSEESRT | ELSRFPNFFN | EIGNDAFDMK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VALKIFNDVA | GSHALANAVF | LLFFNKVDLF | KELLPQVSLQ | PCFSKFAEEN | SYDNTSKFIC |
| 370 | 380 | 390 | 400 | ||
| DKFIRAAKPK | KSVFPHFTTA | TNTENIKMVF | RACMESVFKA | NSKATGLS |