Q4V7N8

PR
Gene name
ciapin1
Protein name
Anamorsin
Names
Cytokine-induced apoptosis inhibitor 1, Fe-S cluster assembly protein DRE2 homolog
Species
Xenopus laevis (African clawed frog)
KEGG Pathway
xla:398841
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

134-211 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q4V7N8

Entry ID Method Resolution Chain Position Source
AF-Q4V7N8-F1 Predicted AlphaFoldDB

No variants for Q4V7N8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4V7N8

No associated diseases with Q4V7N8

1 regional properties for Q4V7N8

Type Name Position InterPro Accession
domain Adaptor protein ClpS, core 19 - 98 IPR003769

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus
  • Mitochondrion intermembrane space
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
mitochondrial intermembrane space The region between the inner and outer lipid bilayers of the mitochondrial envelope.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

5 GO annotations of molecular function

Name Definition
2 iron, 2 sulfur cluster binding Binding to a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands.
4 iron, 4 sulfur cluster binding Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
electron transfer activity Any molecular entity that serves as an electron acceptor and electron donor in an electron transport chain. An electron transport chain is a process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.
metal ion binding Binding to a metal ion.
methyltransferase activity Catalysis of the transfer of a methyl group to an acceptor molecule.

4 GO annotations of biological process

Name Definition
apoptotic process A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
hemopoiesis The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.
iron-sulfur cluster assembly The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.
negative regulation of apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDDLANLVFP GQQVAVTWDG SSSTEALKEF VSKLQEVVAP RGKVSVENIE RLLLSAHADS
70 80 90 100 110 120
SFDAILLGMV QGTQCIHSSE VLAEVARILK PGGALIIQEP VAAGAGAQLR TPEHLSSVLK
130 140 150 160 170 180
LSGLTEVTQL LQEPLNPEQK QGVVELLGYN GNDVSTIRIR AKKPNYEVGS SRQLSLPKRK
190 200 210 220 230 240
TAEKPSVDPA AAKLWTLSAS DMNDDDVDIL DSDELLDQED LKKPAPSSLL ASGCGEGSEK
250 260 270 280 290 300
KRKACKNCTC GLAEELEAEK TPSTVPKAAP SACGNCYLGD AFRCASCPYL GMPAFKPGEK
310
VLLNPTKLQD A