Q4V7K4

PR
Gene name
patl2
Protein name
Protein PAT1 homolog 2
Names
PAT1-like protein 2, Protein P100, Protein PAT1 homolog a, Pat1a, XPat1a
Species
Xenopus laevis (African clawed frog)
KEGG Pathway
xla:443730
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

19-507 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q4V7K4

Entry ID Method Resolution Chain Position Source
AF-Q4V7K4-F1 Predicted AlphaFoldDB

No variants for Q4V7K4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4V7K4

No associated diseases with Q4V7K4

1 regional properties for Q4V7K4

Type Name Position InterPro Accession
domain mRNA decay factor PAT1 domain 442 - 581 IPR019167

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
P-body A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.
ribonucleoprotein complex A macromolecular complex that contains both RNA and protein molecules.

5 GO annotations of molecular function

Name Definition
G-quadruplex RNA binding Binding to a G-quadruplex RNA structure, in which groups of four guanines adopt a flat, cyclic hydrogen-bonding arrangement known as a guanine tetrad.
poly(G) binding Binding to a sequence of guanine residues in an RNA molecule.
poly(U) RNA binding Binding to a sequence of uracil residues in an RNA molecule.
RNA binding Binding to an RNA molecule or a portion thereof.
translation repressor activity Antagonizes ribosome-mediated translation of mRNA into a polypeptide.

3 GO annotations of biological process

Name Definition
deadenylation-dependent decapping of nuclear-transcribed mRNA Cleavage of the 5'-cap of a nuclear mRNA triggered by shortening of the poly(A) tail to below a minimum functional length.
negative regulation of cytoplasmic mRNA processing body assembly Any process that decreases the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.
negative regulation of translation Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNLGSEQILP EDFYLAEEGA LLEEMAEEDE EIDLYNEVTF GLDQESDEEP VKLEDDHTKP
70 80 90 100 110 120
IQMPEAPKEE EPEALQPVKE AKGSEKAPLH EVKIVVEPHE DHVDLSIDSG GHTMNSTMDD
130 140 150 160 170 180
SELGDPAVMK AFHGKPTLES LDSAVVDSGI GSTWSELDTD YDQSGMDSGL WEASPKVSTY
190 200 210 220 230 240
ATGQILEDKA ILRIMERAPY LPPTNLEFLG SPLQRGFMPS QRLQGPEMGA MSPKPYRPRF
250 260 270 280 290 300
MRQQSPLVPR SMRPSYPFTP PRRGPSVFAP NQSPGFVSQT PFRPMSPNVS TPTRPMTPKM
310 320 330 340 350 360
VRMHFGPMSP SPSFSPFFSP MGNALQRFKV PGHVTQLHPQ HRRILSQRQR PQSSSRRQWE
370 380 390 400 410 420
SRPDPYASLM SQKEKEWVIK LQMIQLQSEN PHLDDYYYQA YYENLERKLS EEEFLGERKK
430 440 450 460 470 480
REPTKLVTPY IQKAETYESV VHIEGSLGQV AVSTCYSPRR AIDAVSYAMP DEAIKALGYQ
490 500 510 520 530 540
RLRVLKHAEK VFLMFLEVEE LARKMSHIPE EEHVHFQHKQ NYKVQRIYDV LKIAPCHNEE
550 560 570 580 590 600
ESEFLQLLQV GKGKKLVARL LPFLRSEQAR EILLLVVQHL TFLIKNDSAE ESLSVLYGPL
610 620 630 640 650 660
KTIINGLSFT ELIGVTQELT RPLPESNDLP LTLAFQNQFG ISLLYCLLSH GERLLSSDLP
670 680 690 700 710 720
MEPCIGDFEK WTDTVFLVAK ELSHVSKSSM VEPLFLPSNL LSLFCRYLDK QTIHKLEDKM
730
ECPVIPPYTA VPS