Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q4V7E5

Entry ID Method Resolution Chain Position Source
AF-Q4V7E5-F1 Predicted AlphaFoldDB

No variants for Q4V7E5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4V7E5

No associated diseases with Q4V7E5

2 regional properties for Q4V7E5

Type Name Position InterPro Accession
domain Peptide chain release factor class I 222 - 331 IPR000352
domain Peptide chain release factor 58 - 214 IPR005139

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

1 GO annotations of molecular function

Name Definition
translation release factor activity Involved in catalyzing the release of a nascent polypeptide chain from a ribosome.

1 GO annotations of biological process

Name Definition
mitochondrial translational termination The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa).

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9H3J6 MTRFR Mitochondrial translation release factor in rescue Homo sapiens (Human) PR
Q9UGC7 MTRF1L Peptide chain release factor 1-like, mitochondrial Homo sapiens (Human) PR
10 20 30 40 50 60
MRSGFLRSAR RLWARRAISR MPPPSEELLA RGGPLRAFLE RRVGSEAGGL DAGSPQLAAA
70 80 90 100 110 120
ARLLNEKERE LRDTESLLHD ENEDLKKLAE SEIALCQKEI AELKHRIISL LVPSEDMDGS
130 140 150 160 170 180
DLILEVTAGV GGQEAMLFTS EMFDMYQQYA AFKRWHFETL EYFPSELGGL RHASASIGGP
190 200 210 220 230 240
EAYRHMKFEG GVHRVQRVPK TERQGRIHTS TMTVAILPQP TEIKLVINPK DLRIDTKRAS
250 260 270 280 290 300
GAGGQHVNTT DSAVRIVHLP TGIISECQQE RSQLKNRELA MKKLRARLYS MRLEEETAKR
310 320 330 340 350 360
YSARKIQVGT KGRSEKIRTY NFPQNRVTDH RINKSLHDLE SFMQGDCLLD DLIQSLKDYS
370
DYESLVEMIS RKD