Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q4UWA2

Entry ID Method Resolution Chain Position Source
AF-Q4UWA2-F1 Predicted AlphaFoldDB

No variants for Q4UWA2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4UWA2

No associated diseases with Q4UWA2

6 regional properties for Q4UWA2

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 401 - 570 IPR000795
domain Small GTP-binding protein domain 403 - 560 IPR005225
domain Translation initiation factor IF-2, N-terminal 325 - 375 IPR006847
domain Initiation factor 2 associated domain, bacterial 70 - 105 IPR013575
domain Translation initiation factor IF- 2, domain 3 678 - 792 IPR023115
domain Translation initiation factor IF-2, domain II 576 - 670 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSQQTTIRKL AELVNTPVDK LLVQLAEAGM KFSGPDQVVT STEKMKLLGF LRRTHGKADT
70 80 90 100 110 120
PAEAASEAAK KITLNRRKLQ EVTVNAGRTK TTVNVEVRQK RTYVKSENEG SGRAAPMTPD
130 140 150 160 170 180
EERADILAKL AASRQRNLDE QQRLAESDRA RDEAIQRKRD EEQAAKDRVE AERKAAEEAA
190 200 210 220 230 240
AAASAPAPVA AAPAPSSAPA ARAPSSPSSA PRPARPAGAS PASRPATPAR PDDRNNAAKH
250 260 270 280 290 300
KTRGSHVMVA GVEDDDATKR FAGQLHLSAA DRARRSNVRG KPTGRPGSSS SRRNDGGRGS
310 320 330 340 350 360
NQSNSGPHGF ERPTAPVVRE VAIGETITVA DLAQKLALKG GDVVKALFKM GVMATITQSI
370 380 390 400 410 420
DHDTAALVTE ELGHKAVRAD NADFEDALLA HAEDAQGETT SRPPVVTIMG HVDHGKTSLL
430 440 450 460 470 480
DYIRRTKIAS GEAGGITQHI GAYHVETGRG VISFLDTPGH AAFTSMRARG AKITDIVVLV
490 500 510 520 530 540
VAADDGVMPQ TKEAVAHAKA AGVPLIVAVN KIDKAGADPL RVKNELLAEN VVAEDFGGDT
550 560 570 580 590 600
QFIEVSAKVG TGVDTLLDAI SLQAEVLELK AVADGRASGT VIESSLDKGR GPVATVLVQQ
610 620 630 640 650 660
GALKRGDYLV CGIQYGRVRA LFDETGHQPA SAGPSIPVQV LGLSGVPEAG DDFVVVDDER
670 680 690 700 710 720
LAKDVAQQRE TKRRESRLVA SATNRMEDIL AQMGKGEGQQ VLNLVIKADV QGSVEALKQS
730 740 750 760 770 780
LVALSNDDIR INVIHSGVGG ITESDANSAA ASKATIIGFN VRADASARKI VESNGIDLRY
790 800 810 820 830 840
FSIIYDVIDQ VKQVASGLLG VEIREEIIGI AQVRDVFRSS KFGAVAGCMI IEGVVKRSKP
850 860 870 880 890 900
IRVLRDSVVV FEGELESLRR FKENVDEVRN GTECGIGVKA YNDVKAGDQI ECFERIEVAR
TL