Q4R8M0

PR
Gene name
SLC25A31
Protein name
ADP/ATP translocase 4
Names
ADP,ATP carrier protein 4, Adenine nucleotide translocator 4, ANT 4, Solute carrier family 25 member 31
Species
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-44 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q4R8M0

Entry ID Method Resolution Chain Position Source
AF-Q4R8M0-F1 Predicted AlphaFoldDB

No variants for Q4R8M0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4R8M0

No associated diseases with Q4R8M0

3 regional properties for Q4R8M0

Type Name Position InterPro Accession
repeat Mitochondrial substrate/solute carrier 18 - 113 IPR018108-1
repeat Mitochondrial substrate/solute carrier 122 - 216 IPR018108-2
repeat Mitochondrial substrate/solute carrier 219 - 309 IPR018108-3

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion inner membrane ; Multi-pass membrane protein
  • Membrane ; Multi-pass membrane protein
  • Cell projection, cilium, flagellum membrane ; Multi-pass membrane protein
  • In sperm flagellum this protein is located in the fibrous sheath, a non-mitochondrial region (By similarity)
  • May localize to non-mitochondrial membranes (By similarity)
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

5 GO annotations of cellular component

Name Definition
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
mitochondrial inner membrane The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
mitochondrial permeability transition pore complex A protein complex that connects the inner and outer membranes of animal mitochondria and acts as a pore that can open transiently to allow free diffusion of solutes between the mitochondrial matrix and the cytosol. The pore complex is formed of the voltage-dependent anion channel (VDAC), the adenine nucleotide translocase (ANT) and cyclophilin-D (CyP-D).
motile cilium A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
ATP:ADP antiporter activity Catalysis of the reaction: ATP(out) + ADP(in) = ATP(in) + ADP(out).

6 GO annotations of biological process

Name Definition
cell differentiation The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
male meiosis I A cell cycle process comprising the steps by which a cell progresses through male meiosis I, the first meiotic division in the male germline.
mitochondrial ADP transmembrane transport The process in which ADP is transported across a mitochondrial membrane, into or out of the mitochondrion.
mitochondrial ATP transmembrane transport The process in which ATP is transported across a mitochondrial membrane, into or out of the mitochondrion.
regulation of mitochondrial membrane permeability Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane.
spermatogenesis The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MHREPPKKKA EKRLFDASSF GKDLLAGGVA AAVSKTAVAP IERVKLLLQV QASSKQISPE
70 80 90 100 110 120
ARYKGMVDCL VRIPREQGFF SFWRGNLANV IRYFPTQALN FAFKDKYKQL FMSGVNKEKQ
130 140 150 160 170 180
FWRWFLANLA SGGAAGATSL CVVYPLDFAR TRLGVDIGKG PEERQFKGLG DCIMKIAKSD
190 200 210 220 230 240
GIAGLYQGFG VSVQGIIVYR ASYFGAYDTV KGLLPKPKKT PFLVSFFIAQ VVTTCSGILS
250 260 270 280 290 300
YPFDTVRRRM MMQSGEAKRQ YKGTLDCFVK IYQHEGINSF FRGAFSNVLR GTGGALVLVL
310
YDKIKEFFHI DIGGR