Q4R816

PR
Gene name
LDHAL6B (QtsA-13749)
Protein name
L-lactate dehydrogenase A-like 6B
Names
Species
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
KEGG Pathway
EC number
1.1.1.27: With NAD(+) or NADP(+) as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

24-95 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q4R816

Entry ID Method Resolution Chain Position Source
AF-Q4R816-F1 Predicted AlphaFoldDB

No variants for Q4R816

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4R816

No associated diseases with Q4R816

3 regional properties for Q4R816

Type Name Position InterPro Accession
domain Lactate/malate dehydrogenase, N-terminal 71 - 209 IPR001236
active_site L-lactate dehydrogenase, active site 239 - 245 IPR018177
domain Lactate/malate dehydrogenase, C-terminal 213 - 377 IPR022383

Functions

Description
EC Number 1.1.1.27 With NAD(+) or NADP(+) as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
L-lactate dehydrogenase activity Catalysis of the reaction: (S)-lactate + NAD+ = pyruvate + NADH + H+.

1 GO annotations of biological process

Name Definition
carboxylic acid metabolic process The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSWTVPLVRA SQRVSSVGAN FLCLKMALCP RQAARIPLKG AWRFTSVSKM ATVKSELIER
70 80 90 100 110 120
FTSEEPVHHS KVSIIGTGSV GMACAISILL KGLIDELALV DLDEGKLKGE TMDLQHGSSF
130 140 150 160 170 180
TKMPNIVCSK DYFVTANSNL VIITAGARQE KGETRLNLVQ RNVALFKLMI SNIVQHSPHC
190 200 210 220 230 240
KLIIVSNPVD ILSYVAWKLS AFPKNRVIGS GCNLDTARFR FLIGQKLGIH SESCHGWILG
250 260 270 280 290 300
EHGDSSVPVW SGVNIAGVPL KDLNSDIGTD KDPEQWKNVH EEVIATAYEI IKMKGYTSWA
310 320 330 340 350 360
IGLSVADLTE SILKNLRRTH PVSTIIKGLY GIDEEVFLSI PCILGENGIT HLIKIKLTPE
370 380
EEDRLKKSAK TLWEIQKELK I