Q4R7Y8

PR
Gene name
BBOF1
Protein name
Basal body-orientation factor 1
Names
Coiled-coil domain-containing protein 176
Species
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-233 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q4R7Y8

Entry ID Method Resolution Chain Position Source
AF-Q4R7Y8-F1 Predicted AlphaFoldDB

No variants for Q4R7Y8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4R7Y8

No associated diseases with Q4R7Y8

1 regional properties for Q4R7Y8

Type Name Position InterPro Accession
domain Domain of unknown function DUF4515 77 - 270 IPR032777

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm, cytoskeleton, cilium basal body
  • Cytoplasm, cytoskeleton, flagellum axoneme
  • Localizes to a polar structure adjacent to the basal body
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
ciliary basal body A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport.
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
motile cilium assembly The aggregation, arrangement and bonding together of a set of components to form a motile cilium.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPSKGKDKKK GKSRGKDTKK LIKTDESVVD RAKANASLWE ARLEITELSR IEYRDTSRTL
70 80 90 100 110 120
AKSNEDLKKK QCKMEKDIMS VLSYLKKQDQ EKDNMIEKLK QQLNETKEKA QEEKDKLEQK
130 140 150 160 170 180
YTRQIDELEG QFHQKAKEIG MIHTELKAVR QFQRRKIQVE RELDDLKENL RNTERIHQET
190 200 210 220 230 240
LRRLESRFFE EKHRLKQEAE KKIIMLAERA HHEAVVQLND AGRNVFKENV YLQKALAYHL
250 260 270 280 290 300
KEAGGLQKNS QKLQESHALL LHQKEINDLL IKEKIMQLVQ QRSQIQTLQK KVVNLETALG
310 320 330 340 350 360
YMTKEFESEV LKLQQHAMIE NQAGQVEIDK LQHLLQMKDR EMNRVKKLAK NILDERTEVE
370 380 390 400 410 420
RFFLDALHQV KQQILISRKH YKQIAQAAFN LKMRAACAGR TEYPKIRTFD GREHSTNSVN
430 440 450 460 470 480
QDLLEAEKWT HIEGNVDIGD LTWEQKEKVL RLLFAKMNGC PSRKYNQSSK PPVPDYVVSD
490 500 510 520
SGETKEFGDE SKLQDKIFIT QQIPISDSSG KVVLPTIPKG PQESDTGTF