Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q4R7Y2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q4R7Y2-F1 | Predicted | AlphaFoldDB |
No variants for Q4R7Y2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q4R7Y2 | |||||
No associated diseases with Q4R7Y2
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosolic large ribosomal subunit | The large subunit of a ribosome located in the cytosol. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| structural constituent of ribosome | The action of a molecule that contributes to the structural integrity of the ribosome. |
| translation regulator activity | Any molecular function involved in the initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| embryonic brain development | The process occurring during the embryonic phase whose specific outcome is the progression of the brain over time, from its formation to the mature structure. |
| regulation of translation | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA. |
| translation | The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGRRPARRYR | YCKNKPYPKS | RFCRGVPDAK | IRIFDLGRKK | AKVDEFPLCG | HMVSDEYEQL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SSEALEAARI | CANKYMVKSC | GKDGFHIRVR | LHPFHVIRIN | KMLSCAGADR | LQTGMRGAFG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KPQGTVARVH | IGQVIMSIRT | KLQNKEHVIE | ALRRAKFKFP | GRQKIHISKK | WGFTKFNADE |
| 190 | 200 | 210 | |||
| FEDMVAEKRL | IPDGCGVKYI | PNRGPLDKWR | ALHS |