Q4R7N3
Gene name |
ADAT1 (QtsA-14745) |
Protein name |
tRNA-specific adenosine deaminase 1 |
Names |
tRNA-specific adenosine-37 deaminase |
Species |
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) |
KEGG Pathway |
|
EC number |
3.5.4.34: In cyclic amidines |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q4R7N3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q4R7N3-F1 | Predicted | AlphaFoldDB |
No variants for Q4R7N3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q4R7N3 | |||||
No associated diseases with Q4R7N3
1 regional properties for Q4R7N3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Adenosine deaminase/editase | 2 - 502 | IPR002466 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.5.4.34 | In cyclic amidines |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
| tRNA-specific adenosine deaminase activity | Catalysis of the reaction: adenosine + H2O = inosine + NH3, in a tRNA molecule. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| tRNA processing | The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MWTADEIALL | CYEHYGIRLP | KKGKPEPNHE | WTLLAAVVKI | QSPADQDCDT | PDKPAQVTKE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VVSMGTGTKC | IGQSKMRKSG | DILNDSHAEV | IARRNFQRYL | LHQLQLAATL | KEDSIFVPGT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QKGLWKLRRD | LFFVFFSSHT | PCGDASIIPM | LEFEDQPCCP | VIRDWASSSS | VEASSNLEAP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GNERKCEDLD | SPVTKKMRLE | PMTAAREVTN | GATHHQSFGK | QESGPISPGI | NSCNLTVEGL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AAVTRIAPGS | AKVIDVYRTG | AKCVPGEAGD | SRKPGAAFHQ | VGLLRVKPGR | GDRTRSMSCS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| DKMARWNVLG | CQGALLMHFL | EEPIYLSAVV | IGKCPYSQEA | MQRALTGRRQ | NVSALPKGFG |
| 370 | 380 | 390 | 400 | 410 | 420 |
| VQELKILQSD | LLFEQSRCAV | QAKRADSPGR | LVPCGAAISW | SAVPEQPLDV | TANGFPQGTT |
| 430 | 440 | 450 | 460 | 470 | 480 |
| KKTIGSLQAR | SQISKVELLR | SFQKLLSRIA | RDKWPDSLRV | QKLDTYQDYK | EAASSYQEAW |
| 490 | 500 | ||||
| STLRKQAFGS | WIRNPPDYHQ | FK |