Q4R6X9

PR
Gene name
DRC3 (LRRC48, QtsA-16881)
Protein name
Dynein regulatory complex subunit 3
Names
Leucine-rich repeat-containing protein 48
Species
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

179-262 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q4R6X9

Entry ID Method Resolution Chain Position Source
AF-Q4R6X9-F1 Predicted AlphaFoldDB

No variants for Q4R6X9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4R6X9

No associated diseases with Q4R6X9

4 regional properties for Q4R6X9

Type Name Position InterPro Accession
repeat Leucine-rich repeat 66 - 87 IPR001611-1
repeat Leucine-rich repeat 88 - 109 IPR001611-2
repeat Leucine-rich repeat 110 - 131 IPR001611-3
repeat Leucine-rich repeat 132 - 153 IPR001611-4

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm, cytoskeleton, cilium axoneme
  • Cell projection, cilium
  • Cytoplasm, cytoskeleton, flagellum axoneme
  • Cell projection, cilium, flagellum
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytoskeleton A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
sperm flagellum A microtubule-based flagellum (or cilium) that is part of a sperm, a mature male germ cell that develops from a spermatid.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNRLCDSMEP KVMDDDMLKL AVGEQGPQEE AGQLAKQEGI LFKDVLSLQL DFRNILRIDN
70 80 90 100 110 120
LWQFENLRKL QLDNNIIEKI GGLENLTHLV WLDLSFNNIE TIEGLDTLVN LEDLSLFNNR
130 140 150 160 170 180
ISKIDSLDAL VKLQVLSLGN NQIDNMMNIV YLRRFQCLRT LSLSGNPISE AEDYKMFICA
190 200 210 220 230 240
YLPDLVYLDF RRIDDHTKEL AEAKHQYSID ELKHRENLMQ VRLQDERARQ EELEKHKTAF
250 260 270 280 290 300
VEHLNGSFLF DSMYAEDSEG NKLSYLPGVS ELLEAYKDKF VIICMNIFEY GLKQQEKRKI
310 320 330 340 350 360
ELDTFSECVH EAIQENQEQG KRKIAQFEEK HLSSLSAIRE ESELPNIEKM ILECSADVSE
370 380 390 400 410 420
LFNELMMLEM QLVEQLEETI NMFERNIVDM VGLFIENVQS LMAQCRDLEN HHHEKLLEIS
430 440 450 460 470 480
ISTLEKIVKG DLDEDLPDDL RALFVDKDTI VNAVGASHDI HLLKIDNRED ELVTRINSWC
490 500 510 520
TRLVDKIHKD EIMRNRKRVK EINQYIDHMQ SELDNLEYSD ILD