Q4R6C5

PR
Gene name
ROPN1 (QflA-14788, QtsA-18306)
Protein name
Ropporin-1
Names
Rhophilin-associated protein 1
Species
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

27-103 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q4R6C5

Entry ID Method Resolution Chain Position Source
AF-Q4R6C5-F1 Predicted AlphaFoldDB

No variants for Q4R6C5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4R6C5

No associated diseases with Q4R6C5

No regional properties for Q4R6C5

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q4R6C5

Functions

Description
EC Number
Subcellular Localization
  • Cell projection, cilium, flagellum
  • In the sperm tail, found in the principal piece and in the cytoplasmic droplet located at the distal end of the midpiece
  • Inner surface of the fibrous sheath
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
motile cilium A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

5 GO annotations of biological process

Name Definition
cilium organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
flagellated sperm motility The directed, self-propelled movement of a cilium (aka flagellum) that contributes to the movement of a flagellated sperm.
protein localization to cilium A process in which a protein is transported to, or maintained in, a location within a cilium.
regulation of protein phosphorylation Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.
sperm capacitation A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAQTDKPTCI PPELPKMLKE FAKAAIRAQP QDLIQWGADY FEALSRGETP PVREQSERVA
70 80 90 100 110 120
LCNWAELTPE VLKILHSQVA GRLIVHAEEL AQMWKVVNLP ADLFNSVMNV GRFTEEIEWL
130 140 150 160 170 180
KFLALACSAL GVTITKTLKI VCEVLSCDHN GGLPRIPFST FQFLYTYIAE VDGEISASHV
190 200 210
SRMLNYIEQE VIGPDGLITV NDFTQNPRVW LE