Q4R623

PR
Gene name
DEPDC1B (QtsA-19314)
Protein name
DEP domain-containing protein 1B
Names
Species
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

76-176 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q4R623

Entry ID Method Resolution Chain Position Source
AF-Q4R623-F1 Predicted AlphaFoldDB

No variants for Q4R623

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4R623

No associated diseases with Q4R623

2 regional properties for Q4R623

Type Name Position InterPro Accession
domain Rho GTPase-activating protein domain 201 - 393 IPR000198
domain DEP domain 24 - 108 IPR000591

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
GTPase activator activity Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.

3 GO annotations of biological process

Name Definition
cell migration The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
intracellular signal transduction The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
positive regulation of Wnt signaling pathway Any process that activates or increases the frequency, rate or extent of Wnt signal transduction.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEHRIVGPGP YRATRLWNET VELFRAKMPL RKHRCRFKSY EHCFTAAEAV DWLHELLRCS
70 80 90 100 110 120
QNFGPEVTRK QTVQLLKKFL KNHVIEDIKG KWGQEDFEDN RHLYRFPPSS PLKPYPKKPP
130 140 150 160 170 180
YQKDVIKFPE WNDPPPGTSQ ENIPVRPVVM NSEMWYKRHS IAIGEVPACR LVHRRQLTEA
190 200 210 220 230 240
NVEEIWKSMT LSYLQKILGL DSLEEVLDIK LVNSKFIIHN VYSVSKQGVV ILDDKSKELP
250 260 270 280 290 300
HWVLSAMKCL ANWPNCSDLK QPMYLGFEKD VFKTIADYYG HLKEPLLTFH LFDAFVSVLG
310 320 330 340 350 360
LLQKEKVAVE AFQICCLLLP PENRRKLQLL MRMMARICLN KEMPPLCDGF GTRTLMVQTF
370 380 390 400 410 420
SRCILCSKDE VDLDELLAAR LVTFLMDNYQ EILKVPLDLQ TSIEERVAHL RRVQIKYPGA
430 440 450 460 470 480
DMDITLSAPS FCRQISPEEF EYQRSYGSQE PLAALLEEVI TDAKLSSKEK KKKLKQFQKS
490 500 510 520
YPEVYQERFP TPESEALLFP EKPKPKPQLL MWALKKPFQP FQRTRSFRM