Q4R5Z4

PR
Gene name
INTS9 (QtsA-19691)
Protein name
Integrator complex subunit 9
Names
Int9
Species
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

492-588 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q4R5Z4

Entry ID Method Resolution Chain Position Source
AF-Q4R5Z4-F1 Predicted AlphaFoldDB

No variants for Q4R5Z4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4R5Z4

No associated diseases with Q4R5Z4

2 regional properties for Q4R5Z4

Type Name Position InterPro Accession
domain Proteasome component (PCI) domain 251 - 430 IPR000717
domain Eukaryotic translation initiation factor 3 subunit E, N-terminal 23 - 157 IPR019010

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integrator complex A protein complex that stably associates with the C-terminus of RNA polymerase II and mediates 3'-end processing of small nuclear RNAs generated by RNA polymerase II.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
snRNA processing Any process involved in the conversion of a primary small nuclear RNA (snRNA) transcript into a mature snRNA molecule. The primary function of snRNAs is processing pre-messenger RNA in the nucleus. They have also been shown to aid in the regulation of transcription factors (7SK RNA) or RNA polymerase II (B2 RNA), and maintaining the telomeres.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKLYCLSGHP TLPCNVLKFK STTIMLDCGL DMTSTLNFLP LPLVQSPRLS SLPGWSLKDG
70 80 90 100 110 120
NAFLDKTELI DLSTVDVILI SNYHCMMALP YITEHTGFTG TVYATEPTVQ IGRLLMEELV
130 140 150 160 170 180
NFIERVPKAQ SASLWKNKDI QRLLPSPLKD AVEVSTWRRC YTMQEVNSAL SKIQLVGFSQ
190 200 210 220 230 240
KIELFGAVQV TPLSSGYALG SSNWIIQSHY EKVSYVSGSS LLTTHPQPMD QASLKNSDVL
250 260 270 280 290 300
VLTGLTQIPT ANPDGMVGEF CSNLALTVRN GGNVLVPCYP SGVIYDLLEC LYQYIDSAGL
310 320 330 340 350 360
SSVPLYFISP VANSSLEFSQ IFAEWLCHNK QSKVYLPEPP FPHAELIQTN KLKHYPSIHG
370 380 390 400 410 420
DFSNDFRQPC VVFTGHPSLR FGDVVHFMEL WGKSSLNTVI FTEPDFSYLE ALAPYQPLAM
430 440 450 460 470 480
KCIYCPIDTR LNFIQVSKLL KEVQPLHVVC PEQYTQPPPA QSHRMDLMID CQPPAMSYRR
490 500 510 520 530 540
AEVLALPFKR RYEKIEIMPE LADSLVPMEI KPGISLATVS AVLHTKDNKH LLQPPPRPAQ
550 560 570 580 590 600
PTSGKKRKRV SDDVPDCKVL KPLLSGSIPV EQFVQTLEKH GFSDIKVEDT AKGHIVLLQE
610 620 630
AETLIQIEED STHIICDNDE MLRVRLRDLV LKFLQKF