Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q4R599
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q4R599-F1 | Predicted | AlphaFoldDB |
No variants for Q4R599
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q4R599 | |||||
No associated diseases with Q4R599
No regional properties for Q4R599
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q4R599 | |||
Functions
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| perinuclear region of cytoplasm | Cytoplasm situated near, or occurring around, the nucleus. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| sequence-specific DNA binding | Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| cell differentiation | The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. |
| spermatogenesis | The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSNKEGSGGF | RKRKHDNFPH | NQRREGKDVN | SSSPVMLAFK | SFQQELDARH | DKYERLVKLS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RDITVESKRT | IFLLHRITSA | PDMEDILTES | EIKLDGVRQK | IFQVAQELSG | EDMHQFHRAI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TTGLQEYVEA | VSFQHFIKTR | SLISMDEINK | QLIFTTDDNG | KENKTPSSDT | QDEQFGTWRL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RVTPVDYLLG | VADLTGELMR | MCINSVGNGD | IDTPFEVSQF | LRQVYDGFSF | IGNTGPYEVS |
| 250 | 260 | 270 | 280 | ||
| KKLYTLKQSL | AKVENACYAL | KVRGSEIPKH | MLADVSSVKT | EMIDQEEGIS |