Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q4R537
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q4R537-F1 | Predicted | AlphaFoldDB |
No variants for Q4R537
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q4R537 | |||||
No associated diseases with Q4R537
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| endoribonuclease activity | Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks. |
| metal ion binding | Binding to a metal ion. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| cleavage involved in rRNA processing | Any phosphodiester bond hydrolysis involved in the conversion of a primary ribosomal RNA (rRNA) transcript into a mature rRNA molecule. |
| ribosomal small subunit biogenesis | A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a small ribosomal subunit; includes transport to the sites of protein synthesis. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAPVEHVVAD | AGAFLRDAAL | QDIGKNIYTI | REVVTEIRDK | ATRRRLAVLP | YELRFKEPLP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QYVRLVTEFS | KKTGDYPSLS | ATDIQVLALT | YQLEAEFVGV | SHLKQEPQKV | KVSSSIQHPE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TPLHISGFHL | PSKPKSPQEA | EKGHPACEPE | NLEFSSFMFW | RNPLPSIDHE | LQELLIDRSE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DVPSKEEEEA | ENGFEDRKDD | SDDDGGGWIT | PNNIKQIQQE | LEQCDVPKDV | RVGCVTTDFA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| MQNVLLQMGL | HVLAVNGMLI | REARSYILRC | HGCFKTTSDM | SRVFCAHCGN | KTLKKVSVTV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SDDGALHMHF | SRNPKVLNPR | GLRYSLPTPK | GGKYAVNPHL | TEDQRFPQLR | LSRKARQKTN |
| 370 | 380 | 390 | 400 | 410 | |
| VFAPDYIAGV | SPFVENDVSS | RSATLQVRDS | TLGAGRRRLN | PNASRKKFVK | KR |